Results 61 to 70 of about 1,259,177 (299)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Modeling and Real-Time Scheduling of DC Platform Supply Vessel for Fuel Efficient Operation
, 2017 DC marine architecture integrated with variable speed diesel generators (DGs) has garnered the attention of the researchers primarily because of its ability to deliver fuel efficient operation. This paper aims in modeling and to autonomously perform real-
Balijepalli, VSK Murthy +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Water Quality, nutrients and the European Union’s Water Framework Directive in a lowland agricultural region: Suffolk, south-east England. [PDF]
, 2001 The water quality of 13 rivers in the lowland, agricultural county of Suffolk is investigated using routine monitoring data for the period 1981 to 2006 collected by the Environment Agency of England and Wales (EA), and its predecessors, with particular ...
A.A. Apodaca +7 more
core +3 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Application of 500 kV UPFC in Suzhou southern power grid
The Journal of Engineering, 2019 The implementation of a 500 kV unified power flow controller (UPFC) project in Suzhou southern power grid is reported in this study. The UPFC project has been put into operation at the end of 2017, and has become the largest capacity and highest voltage ...
Xu Wang +6 more
doaj +1 more source
Crystallization in load-controlled shearing flows of monosized spheres
Soft MatterWe perform discrete simulations of granular system in shearing, wall-bounded problems, under a constant load high enough to induce crystallization, and investigate the role of friction on the shear band formation and the system microstructure.
Esma Kurban, Dalila Vescovi, Diego Berzi
openaire +2 more sources
Circulation control lift generation experiment: Hardware development [PDF]
, 1985 A circulation control airfoil and its accompanying hardware were developed to allow the investigation of lift generation that is independent of airfoil angle of attack and relative flow velocity.
Panontin, T. L.
core +1 more source
Boosting thermoelectric efficiency using time-dependent control
, 2015 Thermoelectric efficiency is defined as the ratio of power delivered to the load of a device to the rate of heat flow from the source. Till date, it has been studied in presence of thermodynamic constraints set by the Onsager reciprocal relation and the ...
Hänggi, Peter +4 more
core +1 more source
Performance and wake analysis of rotors in axial flight using computational fluid dynamics [PDF]
, 2017 Flow field around rotors in axial flight is known to be complex especially in steep descent where the rotor is operating inside its own wake. It is often reported that, in this flight condition, the rotor is susceptible to severe wake interactions ...
Barakos, George +1 more
core +5 more sources