Results 71 to 80 of about 991,490 (245)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Integrated electronic control of electro-hydraulic excavators
An electro-hydraulic system is a control system that combines electrical and hydraulic power to operate machinery and equipment. In this type of system, electrical signals are used in place of mechanical force to regulate the flow of hydraulic fluid ...
Clement Wang
doaj +1 more source
On Solving the Load Flow Problem as an Optimization Problem [PDF]
The load flow problem is usually solved as a system of nonlinear equations using gradient based iterative methods. This technical note explains a way in which the load flow problem can be posed in a form of an optimization problem.
Bukhsh, Waqquas
core
Modeling and Real-Time Scheduling of DC Platform Supply Vessel for Fuel Efficient Operation
DC marine architecture integrated with variable speed diesel generators (DGs) has garnered the attention of the researchers primarily because of its ability to deliver fuel efficient operation. This paper aims in modeling and to autonomously perform real-
Balijepalli, VSK Murthy +2 more
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A new hydraulic synchronous scheme in open-loop control: Load-sensing synchronous control
At present, open-loop synchronous control for hydraulic systems widely using synchronous valves has low synchronous accuracy due to weak anti-bias capacity, and is hard to adjust synchronization velocity, so it could not meet the requirements of accurate
Haigang Ding +2 more
doaj +1 more source
Boosting thermoelectric efficiency using time-dependent control
Thermoelectric efficiency is defined as the ratio of power delivered to the load of a device to the rate of heat flow from the source. Till date, it has been studied in presence of thermodynamic constraints set by the Onsager reciprocal relation and the ...
Hänggi, Peter +4 more
core +1 more source
Alleviating Unsteady Aerodynamic Loads with Closed-Loop Flow Control
The practical benefits and issues related to controlling unsteady loads in gusting flows with active flow control actuators are discussed.
David R. Williams, Rudibert King
openaire +1 more source

