Results 91 to 100 of about 991,490 (245)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Studies of advanced transport aircraft [PDF]
Several concepts for possible future airplanes, including all-wing distributed-load airplanes, multibody airplanes, a long-range laminar flow control airplane, a nuclear-powered airplane designed for towing conventionally powered airplanes during long ...
Nagel, A. L.
core +2 more sources
Circulation control lift generation experiment: Hardware development [PDF]
, 1985 A circulation control airfoil and its accompanying hardware were developed to allow the investigation of lift generation that is independent of airfoil angle of attack and relative flow velocity.
Panontin, T. L.
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Implementation of fuzzy logic controller for load frequency control in two area power system [PDF]
, 2014 Currently as there has been an increase in the interconnected systems as far as power systems are concerned. Load as well as power flow in tie-line are varying dynamically.
Rout , Nirakar, Sethy , Jagadish Kumar
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
SSME-HAS dynamic load simulators [PDF]
The space shuttle main engine propellant valve actuators (SSME) were designed to simulate the loads reflected into the SSME by the chamber coolant valve, the fuel preburner, and the oxidizer. The design, and functional description are included along with
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
A Network Flow Model for Price-Responsive Control of Deferrable Load Profiles
Energies, 2018 This paper describes a minimum cost network flow model for the aggregated control of deferrable load profiles. The load aggregator responds to indicative energy price information and uses this model to formulate and submit a flexibility bid to a high ...
Juliano Camargo +2 more
doaj +1 more source