Results 81 to 90 of about 12,777,871 (250)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Current limitations of cryogenic microwave oscillator frequency stability

, 2014
Technical paperCryogenic microwave oscillators built upon sapphire loaded cavity resonators exhibit excellent levels of frequency stability. Here we present an overview of the current understanding of the various processes and noise sources that limit ...
Parker, S., John G. Hartnett, Stephen R. Parker, Ivanov, E., Tobar, M., Michael E. Tobar, Hartnett, J., Eugene N. Ivanov   +7 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Integrated aeroelastic and control analysis of wind turbine blades equipped with microtabs [PDF]

, 2015
This paper presents the results of an investigation into the performance of different controllers in active load control of wind turbine blades equipped with microtabs.
Macquart, Terence, Maheri, Alireza
core   +1 more source

Security load frequency control model of interconnected power system based on deception attack.

PLoS ONE
The interconnected power system connects the power grids of different regions through transmission lines, achieving power interconnection and resource sharing.
Xin Sun, Qiuhang Tang, Qianyi Lu
doaj   +1 more source

Adaptive Event-Triggered Load Frequency Control for Interconnected Microgrids by Observer-Based Sliding Mode Control

IEEE Access, 2019
This paper focuses on the load frequency control (LFC) for a multi-area interconnected microgrid power system with the introduction of communication networks, a robust sliding mode control strategy based on the adaptive event-triggered mechanism is ...
Hongyue Li, Xihuai Wang, Jianmei Xiao
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Optimal feedback path selection for interconnected power systems using load frequency control strategy

, 2020
The main goal of an interconnected power system is to transfer power from one area to another while the network frequency and tie‐line flow remain within the prescribed limits.
Md Alamgir Hossain, Chowdhury, A Hasib, A. Hasib Chowdhury, Md Mijanur Rahman, Rahman, Md Mijanur, Hossain, Md Alamgir   +5 more
core   +1 more source

An Adaptive Internal Model for Load Frequency Control Using Extreme Learning Machine [PDF]

, 2018
As an important part of a power system, a load frequency control has to be prepared with a better controller to ensure internal frequency stability. In this paper, an Internal Model Control (IMC) scheme for a Load Frequency Control (LFC) with an adaptive
Sasaki, Yutaka; Hiroshima University, Chongkai, He; Hiroshima University, Rehiara, Adelhard Beni; Hiroshima University, Zoka, Yoshifumi; Hiroshima University, Yorino, Naoto; Hiroshima University   +4 more
core   +1 more source