Results 101 to 110 of about 2,043,803 (299)

A High-Relative-Bandwidth Doherty Power Amplifier with Modified Load Modulation Network for Wireless Communications. [PDF]

Sensors (Basel), 2023
Zhu H, Zhang Z, Gu C, Xuan X.
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

SiC Varactors for Dynamic Load Modulation of High Power Amplifiers

, 2008
SiC Schottky diode varactors with a high breakdown voltage, a high tuning ratio, and a low series resistance have been designed and fabricated. These characteristics are particularly necessary for the dynamic load modulation of high power amplifiers (PAs)
Fager, Christian, Fager, Christian,, Jos, Hendrikus,, Janzen, Erik, Nilsson, P.-A.,, Jos, Hendrikus, Andersson, K.,, Janzén, Erik,, Rorsman, N.,, Sudow, Mattias,, Nilsson, Per-Åke,, Jos, R.,, Mashad Nemati, Hossein, Gustavsson, Ulf,, Janz\ue9n, Erik, Thorsell, Mattias, Nemati, H.M.,, Rorsman, Niklas, Thorsell, Mattias,, Nilsson, Per-Åke, ul-Hassan, Jawad,, Henry, Anne,, Sudow, M.,, Gustavsson, U.,, Fager, C.,, Andersson, Kristoffer, Gustavsson, Ulf, Rorsman, Niklas,, Südow, Mattias, Thorsell, M.,, Hassan, J,, Jos, Rik, Henry, Anne, Hassan, J, Andersson, Kristoffer,, Mashad Nemati, Hossein,, Nilsson, Per-\uc5ke   +36 more
core   +1 more source

Diagnosis of Combination Faults in a Planetary Gearbox using a Modulation Signal Bispectrum based Sideband Estimator [PDF]

, 2015
This paper presents a novel method for diagnosing combination faults in planetary gearboxes. Vibration signals measured on the gearbox housing exhibit complicated characteristics because of multiple modulations of concurrent excitation sources, signal ...
Gu, Fengshou, Fengshou Gu, Tie Wang, Ball, Andrew D., Rehab, Ibrahim, Gaballa M. Abdallaa, Abdallaa, Gaballa M., Andrew D. Ball, Xiange Tian, Wang, Tie, Tian, Xiange, Ibrahim Rehab, Ball, Andrew   +12 more
core   +1 more source

Autistic traits shape neuronal oscillations during emotion perception under attentional load modulation. [PDF]

Sci Rep, 2023
Duville MM, Ibarra-Zarate DI, Alonso-Valerdi LM.   +2 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Dietary Acid Load Modulation of Asthma-Related miRNAs in the Exhaled Breath Condensate of Children. [PDF]

Nutrients, 2022
Mendes FC, Paciência I, Cavaleiro Rufo J, Silva D, Delgado L, Moreira A, Moreira P.   +6 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Functional working-memory related correlates in PD and controls during load-related modulation.

, 2013
A–B) Regions showing significantly lower load-related modulation in PD during the encoding phase A) and delayed recall B). C) Regions showing significantly higher load-related modulation in PD relative to healthy controls during delayed recall.
Imis Dogan (404796), Kathrin Reetz (295803), Jörg B. Schulz (123442), Claudia Rottschy (404795), Robert Langner (194089), Martin Kronenbuerger (404798), Cornelius Werner (404799), Shahram Mirzazade (404797), N. Jon Shah (404800), Simon B. Eickhoff (138960), Alexandra Kleiman (357389)   +10 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source