Results 41 to 50 of about 2,043,803 (299)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
IEEE AccessThis study proposes a novel dual input power amplifier (PA) with a frequency-periodic load modulated output matching network supported by a broadband biasing network.
Takuma Torii +3 more
doaj +1 more source
Specific sensorimotor interneuron circuits are sensitive to cerebellar-attention interactions
Frontiers in Human Neuroscience, 2022 Background: Short latency afferent inhibition (SAI) provides a method to investigate mechanisms of sensorimotor integration. Cholinergic involvement in the SAI phenomena suggests that SAI may provide a marker of cognitive influence over implicit ...
Jasmine L. Mirdamadi, Sean K. Meehan
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
ChipsThis paper presents a comprehensive review of GaAs HBT-based Doherty power amplifiers (DPAs) targeting 5G New Radio (NR) handset applications. Focusing on the critical challenges of linearity enhancement, back-off efficiency improvement, bandwidth ...
Shihai He, Huan Chen
doaj +1 more source
IEEE Access, 2019 In this paper, space vector pulse width modulation (SVPWM)-based algorithms for a five-phase open-end load fed from dual matrix converter (DMC) have been proposed.
Khaliqur Rahman +4 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
, 2014 The relationships between phase distortion, bias point and load modulation in power amplifiers are experimentally evaluated for two different GaN HEMT technologies.
Pirola, M +22 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source