Results 51 to 60 of about 129,952 (301)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Performance Enhancement of Dual-Input Frequency-Periodic Load Modulated Power Amplifier at 1–5.7-GHz Bandwidth With Co-Designed Biasing Network

IEEE Access
This study proposes a novel dual input power amplifier (PA) with a frequency-periodic load modulated output matching network supported by a broadband biasing network.
Takuma Torii, Yuji Komatsuzaki, Shintaro Shinjo, Ryo Ishikawa   +3 more
doaj   +1 more source

Specific sensorimotor interneuron circuits are sensitive to cerebellar-attention interactions

Frontiers in Human Neuroscience, 2022
Background: Short latency afferent inhibition (SAI) provides a method to investigate mechanisms of sensorimotor integration. Cholinergic involvement in the SAI phenomena suggests that SAI may provide a marker of cognitive influence over implicit ...
Jasmine L. Mirdamadi, Sean K. Meehan
doaj   +1 more source

Behavioral modeling of RF PAs under wideband load modulation

, 2017
This work proposes a behavioral modeling approach suitable for power amplifier (PA) operation under dynamic load modulation. The model accounts for the PA nonlinear dynamic effects by means of 1st order kernel functions of the modified Volterra ...
Lukasik, Konstanty, Gibiino, Gian Piero, Schreurs, Dominique, Alberto Santarelli, Konstanty Lukasik, Barmuta, Pawel, Dominique Schreurs, Fabio Filicori, Filicori, Fabio, Pawel Barmuta, Gian Piero Gibiino, Santarelli, Alberto   +11 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Advanced Doherty Power Amplifier Architectures for 5G Handset Applications: A Comprehensive Review of Linearity, Back-Off Efficiency, Bandwidth, and Thermal Management

Chips
This paper presents a comprehensive review of GaAs HBT-based Doherty power amplifiers (DPAs) targeting 5G New Radio (NR) handset applications. Focusing on the critical challenges of linearity enhancement, back-off efficiency improvement, bandwidth ...
Shihai He, Huan Chen
doaj   +1 more source

Performance Analysis of a Three-to-Five Phase Dual Matrix Converter Based on Space Vector Pulse Width Modulation

IEEE Access, 2019
In this paper, space vector pulse width modulation (SVPWM)-based algorithms for a five-phase open-end load fed from dual matrix converter (DMC) have been proposed.
Khaliqur Rahman, Atif Iqbal, Mohammed A. Al-Hitmi, Obrad Dordevic, Salman Ahmad   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Optimization and Improvement of Frequency Modulation Auxiliary Service Control System for the 700 MW Unit

南方能源建设, 2021
[Introduction] The DCS system of two 700 MW units adopting "constant-sliding-constant" variable pressure operation mode in Zhuhai Power Plant adopts DIASYS Netmation distributed control system, which is provided by Mitsubishi company of Japan. At present,
LI Qiang
doaj   +1 more source