Results 141 to 150 of about 3,858,842 (297)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Mechanical load monitoring in rugby: limitations and future perspectives. [PDF]

Front Sports Act Living
Osgnach C, di Prampero PE, Botter A, Maniera M, Morin JB, Pavei G.   +5 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Use of artificial neural networks for helicopter load monitoring

, 2011
The operational loads experienced by rotary-wing aircraft are more complex than those of fixed-wing aircraft due to the dynamic rotating components operating at high frequencies.
Martinez, Marcias, Liu, Andrew, Cheung, Catherine   +2 more
core   +1 more source

Non-Intrusive Load Monitoring Based on Multi-Feature Fusion and Combinatorial Optimization Networks. [PDF]

Sensors (Basel)
Wang Y, Zhang S, Cheng Z.
europepmc   +1 more source

Load Estimation for Distribution Feeder Monitoring & Management

, 2010
Load Estimation is an indispensable tool for distribution system studies, since knowledge of load profiles along the feeder has direct influence on system planning and operation activities.
Singh, Urvir
core  

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

A Retrospective Weekly Rating of Perceived Exertion Measure May Assist Training Load Monitoring in Professional Tennis Players. [PDF]

Sports (Basel)
Méndez DH, Villalba FJ, Soliño S, Gabbett TJ.   +3 more
europepmc   +1 more source

Vehicle Driver Monitoring: sleepiness and cognitive load

, 2017
To prevent road crashes, it is important to understand driver related contributing factors. The overall aim of the Vehicle Driver Monitoring project was to advance the understanding of two such factors; sleepiness and cognitive distraction.
Barua, Shaibal,, Svanberg, Bo,, Ahmed, Mobyen Uddin,, Anund, Anna,, Lindén, Per,, Nilsson, Emma,, Fors, Carina,, Begum, Shahina,, Ahlström, Christer   +8 more
core  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source