Results 121 to 130 of about 278,966 (304)

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

An Automated Load Restoration Approach for Improving Load Serving Capabilities in Smart Urban Networks

Urban Science
In this paper, a very fast and reliable strategy for load restoration utilizing optimal distribution feeder reconfiguration (DFR) is developed. The automated network configuration switches can improve the resilience of a microgrid (MG) equipped with a ...
Ali Esmaeel Nezhad, Mohammad Sadegh Javadi, Farideh Ghanavati, Toktam Tavakkoli Sabour   +3 more
doaj   +1 more source

Component Outage Estimation based on Support Vector Machine

, 2018
Predicting power system component outages in response to an imminent hurricane plays a major role in preevent planning and post-event recovery of the power system.
Eskandarpour, Rozhin, Khodaei, Amin
core   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Multi-Agent Deep Reinforcement Learning for Distributed Load Restoration

IEEE Transactions on Smart Grid
This paper addresses the load restoration problem after power outage events. Our primary proposed methodology is using multi-agent deep reinforcement learning to optimize the load restoration process in distribution systems, modeled as networked microgrids, via determining the optimal operational sequence of circuit breakers (switches).
Linh Vu, Tuyen Vu, Thanh Long Vu, Anurag Srivastava   +3 more
openaire   +2 more sources

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Quantifying the Earthquake Risk to the Electric Power Transmission System in Los Angeles at the Census Tract Level

IEEE Access
This paper develops a probabilistic earthquake risk assessment for the electric power transmission system in the City of Los Angeles. Via a dc load flow analysis of a suite of damage scenarios that reflect the seismic risk in Los Angeles, we develop a ...
Boyu Cheng, Linda Nozick, Ian Dobson, Rachel Davidson, Denis Obiang, Jose Dias, Michael Granados   +6 more
doaj   +1 more source

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Elimination methods of resource allocation deadlock for optical networking real-time connection restoration

Tongxin xuebao, 2008
The arrival of intelligent optical networking highlighted the unusual issue of distributed parallel deadlock in the allocation of resources and impacted on the performance of connection restoration.
LU Yue-ming, ZHAO Tong, GONG Wei-li, LI Hui, JI Yue-feng   +4 more
doaj   +2 more sources