Results 41 to 50 of about 1,221,623 (254)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
ANALYSIS OF LOAD TRANSFER INTO COMPOSITE STRUCTURE [PDF]
The paper presents advantages and disadvantages of metal foils insertion between composite layers. Composites are complex materials of anisotropic structure leading to various failure mechanisms.
Elżbieta SZYMCZYK +2 more
doaj
Study on Vertical Load-Carrying Capacity of Post-Grouting Bored Piles
The relationship between pile side frictional resistance and pile tip resistance and settlement is assumed to be ideal elastic–plastic. The load-transfer method is used to analyze the load-bearing characteristics of bored pile in actual projects, and the
Dezhi Kong, Heng Li, Wensong Gan
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time evolution of damage under variable ranges of load transfer
We study the time evolution of damage in a fiber bundle model in which the range of interaction of fibers varies through an adjustable stress transfer function recently introduced.
B.D. Coleman +38 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Joint admission control algorithm based on load transfer in heterogeneous networks
A load-transfer-based joint admission control (LJAC) algorithm in heterogeneous networks was proposed.The access requirements of users were admitted based on load balancing,the dynamic load transfer of traffics in the overlapping coverage areas of ...
Weiwei XIA, Zhaoming DING, Lianfeng SHEN
doaj
The amputee population according to the World-Health-Organization is about 40 million. However, there is a high abandon rate of socket prostheses for the lower limb (25%–57%).
Giulia Galteri, Luca Cristofolini
doaj +1 more source
Performance analysis of adaptive scheduling in integrated services UMTS networks [PDF]
For an integrated services UMTS network serving speech and data calls, we propose, evaluate and compare different scheduling schemes, which dynamically adapt the shared data transport channel rates to the varying speech traffic load.
Berg, Hans van den, Litjens, Remco
core +2 more sources

