Results 61 to 70 of about 1,221,101 (305)
, 2000 We introduce a continuous damage fiber bundle model that gives rise to macroscopic plasticity and compare its behavior with that of dry fiber bundles. Several interesting constitutive behaviors are found in this model depending on the value of the damage
Herrmann, Hans J. +2 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Pilot Project - Demonstration of Load Rating Capabilities through Physical Load Testing: Tech Transfer Summary, RB32-013, 2013 [PDF]
, 2013 This project demonstrated the capabilities for load testing bridges in Iowa, developed and presented a webinar to local and state engineers, and produced a spreadsheet and benefit evaluation matrix that others can use to preliminarily assess where bridge
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Effect factors of part-load performance for various Organic Rankine cycles using in engine waste heat recovery [PDF]
, 2018 The Organic Rankine Cycle (ORC) is regarded as one of the most promising waste heat recovery technologies for electricity generation engines. Since the engine usually operates under different working conditions, it is important to research the part-load ...
Feng, W +5 more
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Load transfer-crack width relation of non-dowelled jointed plain concrete short slabs
The Baltic Journal of Road and Bridge Engineering, 2018 Non-dowelled short slabs are a cost-effective innovation of jointed plain concrete pavements. The development of this innovation has been concentrated in their structural performance.
Mauricio Pradena, Lambert Houben
doaj +1 more source
Heat flux evaluation in high temperature ring-on-ring contacts [PDF]
, 2014 A comprehensive methodology to investigate heat flux in a ring-on-ring tribometer is presented. Thermal fluxes under high contact pressures and temperature differences were evaluated through an experimental campaign and by a numerical procedure of ...
Arizzi, F, Dini, D, Rizzi, E, Tavasci, A
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source