Results 71 to 80 of about 3,483,119 (301)
Yantu gongcheng xuebao, 2019 Excavation collapses occur frequently, including the excavations supported by steel-braced retaining system. Due to the complex mechanics characteristics of the retaining structures, the influences of partial failures on the overall safety performance ...
ZHENG Gang 1,2, LEI Ya-wei 1,2, CHENG Xue-song 1,2, LI Xi-yuan 1,2, YU Dan-yao 1,2
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Fully grouted rock bolts, anchored using resin or cementitious grout, are widely used in mining and civil engineering to transfer loads from unstable rock to more competent strata, preventing further deformation.
Motallebiyan, Amin
core +1 more source
Experimental determination of natural convection heat transfer coefficients in an attic shaped enclosure [PDF]
, 2010 Heat transfer by natural convection in triangular enclosures is an area of significant importance in applications such as the design of greenhouses, attics and solar water heaters.
Carson, James K. +2 more
core +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Trajectory Tracking Control Strategy of 20-Ton Heavy-Duty AGV Considering Load Transfer
Applied SciencesDuring the operation of outdoor heavy-duty Automated Guided Vehicle (AGV), the stability and safety of AGV are easily reduced due to load transfer.
Xia Li +5 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source