Results 51 to 60 of about 238,837 (270)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Neural controlled differential equations for residential heating load prediction

Journal of Physics: Conference Series
Abstract State of the art control schemes for residential HVAC systems are underutilized due to the small margins of improvement compared to the modeling costs. This study explores the application of neural controlled differential equations (NCDEs) as a data-driven approach to predict baseboard energy usage in residential heating ...
Gabriel Sabbagh, Massimo Cimmino, Benoit Delcroix   +2 more
openaire   +1 more source

Solid medium thermal engine [PDF]

, 1974
A device is described which uses a single phase metallic working substance to convert thermal energy directly into mechanical energy. The device consists of a cylindrical metal tube which is free to rotate about its axis while being subjected to ...
Beam, R. M., Guist, L. R., Jedlicka, J. R.   +2 more
core   +1 more source

Heat conduction in graphene flakes with inhomogeneous mass interface

, 2011
Using nonequilibrium molecular dynamics simulations, we study the heat conduction in graphene flakes composed by two regions. One region is mass-loaded and the other one is intact.
Alaghemandi M, Alaghemandi M, Brenner D W, Cheh J Zhao H, Cheh J Zhao H, Hong Zhao, Jigger Cheh, Ouyang T, Wei N, Wen Z, Wu G   +10 more
core   +1 more source

A review of acid recovery from acidic mining waste solutions using solvent extraction [PDF]

, 2018
This is the peer reviewed version of the following article: Uchenna Kesieme, Andreas Chrysanthou, Maurizio Catulli, and Chu Yong Cheng, ‘A review of acid recovery from acidic mining waste solutions using solvent extraction’, Journal of Chemical ...
Catulli, Maurizio, Cheng, Chu Yong, Chrysanthou, Andreas, Kesieme, Uchenna   +3 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Regeneration experiments below 10K in a regenerative-cycle cryocooler [PDF]

, 1983
At temperatures below 10K, regenerative cycle cryocoolers are limited by regeneration losses in the helium working fluid which result from the decreasing heat capacity of the regenerating material and the increasing density of helium.
Paulson, D. N., Sager, R. E.
core   +1 more source

Analysis of coupled heat and moisture transfer in masonry structures

, 2008
Evaluation of effective or macroscopic coefficients of thermal conductivity under coupled heat and moisture transfer is presented. The paper first gives a detailed summary on the solution of a simple steady state heat conduction problem with an emphasis ...
B Tomková, C Boutin, H Künzel, I Oezdemir, J Auriault, J Grunewald, J Novák, J Philip, J Zeman, Jan Sýkora, Jan Vorel, Jiří Šejnoha, M Biot, M Hassanizadech, M Hassanizadech, M Kaminski, Michal Šejnoha, R De Boer, R Schirmer, R Černý, RW Lewis, Tomáš Krejčí   +21 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source