Results 191 to 200 of about 6,457,110 (386)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Current State of Evidence for Implant Placement and Loading in Partially Edentulous Patients: A Systematic Review. [PDF]

Clin Implant Dent Relat Res
Gallucci GO, Hamilton A, Akhondi S, Pala K, Peña-Cardelles JF.   +4 more
europepmc   +1 more source

Piezoresistive Effect of Plain-weave CFRP Fabric Subjected to Cyclic Loading

, 2016
Yusuke Nishio, Akira TODOROKI, Yoshihiro Mizutani, Yoshiro Suzuki   +3 more
openalex   +2 more sources

Load Distribution Characteristics and Construction Stage Analysis of a Fully Integral Railroad Bridge with End-Restraining Abutment [PDF]

, 2018
Byung‐Ho Choi, Jaeyoung Kwak, Tae-Gon Kim, Cheolsu Lim   +3 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

GNSS evaluation of GRACE-assimilated water storage models over 89 river basins worldwide. [PDF]

Sci Rep
Abbaszadeh M, van Dam T.
europepmc   +1 more source

Automobile Liability Insurance: Loading and Un-Loading in New York [PDF]

, 1962

core   +1 more source

Experimental investigation of model piles subject to lateral load in cohesionless soil [PDF]

Nabaa A. Al-Fahham, Ali A. Al-Jazaairry
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

A Semi-Analytical Loaded Contact Model and Load Tooth Contact Analysis Approach of Ease-Off Spiral Bevel Gears

Yuhui Liu, Liping Chen, Xian Mao, Duansen Shangguan   +3 more
openalex   +1 more source