Results 231 to 240 of about 1,653,673 (316)

Influence of Restorative Material Properties on Dentin Stress Distribution: A 3D Finite Element Analysis of Bioflx and Zirconia Crowns. [PDF]

J Funct Biomater
Bardakci E, Aydin G, Celikel P.
europepmc   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Biomechanical evaluation of biodegradable zinc and polylactide pins for radial head fracture fixation: a human cadaver study. [PDF]

J Orthop Surg Res
Maier JP, Pohl L, Eck J, Erdle B, Mühlenfeld N, Reising K, Seidenstuecker M, Schmal H, Wagner FC.   +8 more
europepmc   +1 more source

Correction to “Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors”

Molecular Oncology, EarlyView.
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

The E. coli DnaX clamp loader sharply bends DNA to load β-clamp at nicks and small gaps. [PDF]

Mol Cell
Zheng F, Yao NY, Georgescu RE, Lyu M, O'Donnell ME, Li H.   +5 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Influence of Framework Material on Stress, Fatigue, and Stability of "All-on-Four" System Components-Biomechanical Evaluation with Finite Element Analysis. [PDF]

J Funct Biomater
Popovic Grubac D, Bozovic D, Lecic J, Kovacic I, Janjic Pavlovic O, Zuza A, Krsticevic D, Ivkovic N.   +7 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Bacillus subtilis immobilization on biochars produced from different feedstocks and pyrolysis temperatures: performance, mechanisms, and salt tolerance. [PDF]

Bioresour Bioprocess
Jiang Z, Liu B, Chen R, Zhang L, Chen G.
europepmc   +1 more source