Results 241 to 250 of about 1,653,673 (316)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Comparing Outcomes of ACL Reconstruction with and Without Cyclic Graft Loading: A Two-Year Minimum Follow-Up Study. [PDF]

J Clin Med
Murgier J, Tourcher T, Cabarkapa S.
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Development of an Instrumented Climbing Hold with an Embedded Six-Axis Force Sensor for Speed Climbing. [PDF]

Sensors (Basel)
Kawamura A, Shintani T, Aihara S, Kurazume R.   +3 more
europepmc   +1 more source

Cerebellar structure is abnormal in schizophrenia and deviates from bipolar disorder. [PDF]

Neuroimage Clin
Rashidi M, Morales J, Brodnick Z, Calhoun VD, Wolf RC, Mueller BA, Demro C, Sponheim SR, Turner JA.   +8 more
europepmc   +1 more source

EXPRESSION OF CONCERN: DIMP53‐1: A Novel Small‐Molecule Dual Inhibitor of p53–MDM2/X Interactions with Multifunctional p53‐Dependent Anticancer Properties

Molecular Oncology, EarlyView.
wiley   +1 more source

The High Solid Loading and Stability of SiO₂ Ceramic Slurry for Stereolithography. [PDF]

Materials (Basel)
Zhang W, Huang C, Xia S, Hu X, Li Q.
europepmc   +1 more source

Effect of Crack Geometry on Tensile Deformation and Local Strain Evolution in X46 Pipeline Steel Thin-Walled Tubes. [PDF]

Materials (Basel)
Yan H, Su M, Luo F, Jiang R.
europepmc   +1 more source