Results 241 to 250 of about 3,130,473 (287)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Artificial intelligence modeling and investigation of metal organic frameworks in drug delivery: modeling of loading capacity and toxicity behavior. [PDF]

Front Chem
Qin Y, Li S, Iqbal J, Shirazian S.
europepmc   +1 more source

Correction to “Altered splicing of ATG16‐L1 mediates acquired resistance to tyrosine kinase inhibitors of EGFR by blocking autophagy in non‐small cell lung cancer”

Molecular Oncology, EarlyView.
wiley   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

The effect of increased weight loading on body weight is partly dependent on Piezo1 in osteoblast-lineage cells and TrkA signaling. [PDF]

Sci Rep
Hägg D, Li L, Beeve AT, Scheller EL, Bellman J, Anesten F, Zlatkovic J, Dalmau Gasull A, Font-Gironès F, Movérare-Skrtic S, Jansson JO, Ohlsson C.   +11 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Comparative Stress Analysis of Maxillary Implant Prostheses With Different Retention Designs and Restorative Materials. [PDF]

Cureus
Singh AR, Kumar S, Aggarwal R, Sharma R, Deokate A, Kaur H, Sra IK.   +6 more
europepmc   +1 more source

Reactive power planning based on a proposed voltage stability index in power systems with renewable energy resources. [PDF]

Sci Rep
Sonbol M, Abdalla OH, Shaheen AM, Fayek HH.   +3 more
europepmc   +1 more source

Age-Dependent Variation in Blood Biopterin Peaks Following Oral Tetrahydrobiopterin Administration in Phenylketonuria. [PDF]

J Inherit Metab Dis
Kitayama K, Sakaguchi T, Nakano N, Kabata D, Shintaku H, Hamazaki T.   +5 more
europepmc   +1 more source

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Loads and load distribution

2022
This chapter has been developed from that authored by Dr M. J. Ryall in the 1st edition published in 2000, much of which remains applicable to bridges today. While permanent dead load and superimposed dead loads are covered, it deals primarily with the intensity and application of the transient loads on bridge structures according to European, British ...
openaire   +1 more source