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Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Constitutive modelling of the behaviour of clays under cyclic loading
Includes bibliography.This research work involved the implementation of a constitutive model based on plasticity theory to model the behaviour of a clay under cyclic loading.
Sellers, E J
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S.42.1-42.3The assessment of multiaxial stress states is already a very difficult subject for constant amplitude loading. If the stresses occur additionally at random, the assessment procedure becomes even more complex, because the design engineer is ...
Störzel, K. +3 more
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Monopiles subjected to uni- and multi-lateral cyclic loading [PDF]
Offshore structures are subjected to significant environmental loads from a combination of current, wind and wave action. Under such conditions, the directions of these environmental loads vary over the service life of the structure and therefore the ...
Sivakumar, Vinayagamoothy +10 more
core +1 more source
The true triaxial apparatus is an ideal instrument to study the mechanical properties of soil under complex stress state, but how to keep the loading structure and soil without friction and independent loading in three directions is the technical ...
Yanli WANG +4 more
doaj
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley +1 more source
ObjectivesThe horizontal load-bearing mechanism of rock-socketed single piles under different loading paths remains unclear. Therefore, this study investigates the load-bearing behavior of rock-socketed piles subjected to multidirectional horizontal ...
Zheng Can +8 more
doaj +1 more source
Finite Element Analysis of Ventilation System Fire Damper Dynamic Time-History
The paper presents results of the numerical analysis of the fire damper used in ventilation systems under the earthquake loading. The research was conducted in accordance with the recommendations of the Nuclear Safety Standards Commission. The aim of the
Skibicki Ł Dariusz +2 more
doaj +1 more source
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley +1 more source
The performance of beam-to-column connections subjected to reversed cyclic loading depends on several variables. In this investigation, the effects of eccentric spandrel beams, wide normal beams, column section aspect ratio, loading in two principal ...
Burak Bakır, Burcu +2 more
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