Results 61 to 70 of about 696,058 (264)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
BuildingsHigh-pile wharves are commonly used on deep soft soil foundations and are prone to the influence of complex environmental factors during long-term service. However, there is limited research on the spatiotemporal coupling effects of complex environmental
Kezheng Yang +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
آلودگیهای محیطی و توسعه پایدار شهریThe physical expansion of a city, when not properly aligned with its natural and historical structures, can lead to failures in urban development processes, particularly in cities with distinctive natural features. Kerman, one of Iran's historical cities
Mohammad Dabdabeh +2 more
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Fractal and FractionalAs mining progresses, complexities arise, leading to potential coal-rock gas dynamic disasters triggered by mining disturbances. These dynamic phenomena are influenced by factors such as loading mode, coal properties, and the presence of gas.
Peng Zou +4 more
doaj +1 more source
Sepa, 2018 The purpose of this research was to know factors that considered by consumer and reviewing dominant variables affecting consumers consideration toward repeat purchase decision on Kalimilk product in Yogyakarta.
Novi Afriyani +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Equivalent method for assessment of bearings at operational types of loadings
Advances in Mechanical EngineeringTo investigate the effect of various factors on bearing stress response, Huber-Hencky-von Mises stress serves as a bridge, the equivalent interrelation between radial loading, axial loading, and temperature of bearing is studied using finite element ...
Shuancheng Wang +4 more
doaj +1 more source
Conventional versus immediate implant loading: When and why
Indian Journal of Dental ResearchObjectives: To review clinical indications, biological considerations, and outcomes associated with conventional and immediate implant loading protocols and to highlight factors influencing successful osseointegration.
Rishika Tiwari
doaj +1 more source