Results 81 to 90 of about 696,058 (264)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Factors Involved in Sludge Granulation under Anaerobic Conditions [PDF]

open access: yesآب و فاضلاب, 2011
This paper investigates the effects of factors involved in sludge anaerobic granulation. Granulated sludge formation is the main parameter contributing to the success of UASB reactors.
Jalal Shayegan   +2 more
doaj  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Peculiarities of Designing the Frame of a Universal Container Made of Rectangular Pipes

open access: yesCommunications
The features of designing the frame of a universal container made of square pipes are presented in this paper. The two frame loading schemes are taken into account: the effect of vertical loading on the container frame when it is lifted by the upper ...
Juraj Gerlici   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Biomechanical Risk Factors for Increased Anterior Cruciate Ligament Loading and Injury: A Systematic Review

open access: yesOrthopaedic Journal of Sports Medicine
Background: Understanding the biomechanical risk factors for noncontact anterior cruciate ligament (ACL) injury can inform machine learning models, aid in prevention strategies, and guide rehabilitation protocols, reducing the incidence and burden of ...
Malachy Belkhelladi BA   +2 more
doaj   +1 more source

Handling and loading market-ready turkeys – Focus groups exploring the perspectives of live haul crew workers in the turkey industry

open access: yesJournal of Applied Poultry Research
Summary: Improper handling and loading of market-ready turkeys during live haul presents significant challenges in the U.S. turkey industry. Bird injuries, such as bruises, scratches, and/or fractured or broken bones compromise animal welfare and lead to
Luz A. Hernandez   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Fatigue life prediction of asphalt binders under variable loading levels based on dissipated pseudo-strain energy

open access: yesCase Studies in Construction Materials
Miner’s criterion is popularized to develop the conventional fatigue life prediction model for estimating the service life corresponding to fixed loading level. However, the conventional model makes it difficult to recognize the significant dependency of
Chenze Fang   +4 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

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