Results 81 to 90 of about 697,307 (264)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier   +11 more
wiley   +1 more source

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala   +8 more
wiley   +1 more source

Factors Involved in Sludge Granulation under Anaerobic Conditions [PDF]

open access: yesآب و فاضلاب, 2011
This paper investigates the effects of factors involved in sludge anaerobic granulation. Granulated sludge formation is the main parameter contributing to the success of UASB reactors.
Jalal Shayegan   +2 more
doaj  

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas   +3 more
wiley   +1 more source

Biomechanical Risk Factors for Increased Anterior Cruciate Ligament Loading and Injury: A Systematic Review

open access: yesOrthopaedic Journal of Sports Medicine
Background: Understanding the biomechanical risk factors for noncontact anterior cruciate ligament (ACL) injury can inform machine learning models, aid in prevention strategies, and guide rehabilitation protocols, reducing the incidence and burden of ...
Malachy Belkhelladi BA   +2 more
doaj   +1 more source

Handling and loading market-ready turkeys – Focus groups exploring the perspectives of live haul crew workers in the turkey industry

open access: yesJournal of Applied Poultry Research
Summary: Improper handling and loading of market-ready turkeys during live haul presents significant challenges in the U.S. turkey industry. Bird injuries, such as bruises, scratches, and/or fractured or broken bones compromise animal welfare and lead to
Luz A. Hernandez   +6 more
doaj   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz   +7 more
wiley   +1 more source

Peculiarities of Designing the Frame of a Universal Container Made of Rectangular Pipes

open access: yesCommunications
The features of designing the frame of a universal container made of square pipes are presented in this paper. The two frame loading schemes are taken into account: the effect of vertical loading on the container frame when it is lifted by the upper ...
Juraj Gerlici   +3 more
doaj   +1 more source

Improvement of Sickle Cell Disease Care Mitigates the Healthcare Utilization Induced by Increased Prevalence: Experience of a Tertiary Pediatric Center

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) has undergone major changes in the last decades. Its prevalence has been steadily increasing and numerous advances have been made in the management of the disease. However, the effect in real‐life setting of these major changes is unknown, particularly in a Canadian environment. Procedure We aimed to assess
Maude Cigna   +16 more
wiley   +1 more source

Fatigue life prediction of asphalt binders under variable loading levels based on dissipated pseudo-strain energy

open access: yesCase Studies in Construction Materials
Miner’s criterion is popularized to develop the conventional fatigue life prediction model for estimating the service life corresponding to fixed loading level. However, the conventional model makes it difficult to recognize the significant dependency of
Chenze Fang   +4 more
doaj   +1 more source

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