Results 51 to 60 of about 44,974 (261)

A 3D‐Printed Vascular‐Like Perfusion Tumor‐on‐a‐Chip Recapitulates High‐Grade Breast Cancer With in Vivo‐Relevant Drug Resistance

Advanced Healthcare Materials, EarlyView.
A high‐resolution 3D‐printed tumor‐on‐a‐chip platform sustains breast cancer tissues at in vivo–like cell densities through vascular‐like perfusion. This engineered system recapitulates grade‐dependent molecular features and exhibits drug‐resistance profiles that uniquely align with clinically relevant Cmax values.
Geonhui Lee, Bingjie Sun, Nicholas X. Fang, Chunguang Xia   +3 more
wiley   +1 more source

Tongue-Yoga: Precision Visual Feedback Rehabilitation Improves Tongue Agility

IEEE Transactions on Neural Systems and Rehabilitation Engineering
The tongue is a uniquely agile muscular structure essential for vital tasks of speech, breathing, chewing, and swallowing, functions commonly disrupted following neurological injury.
Andrea Scarpellini, Lorenzo Di Silverio, Anna Carroll, Leora R. Cherney, Edna M. Babbitt, James L. Patton, Hananeh Esmailbeigi   +6 more
doaj   +1 more source

CHROMATIX: computing the functional landscape of many-body chromatin interactions in transcriptionally active loci from deconvolved single cells

Genome Biology, 2020
Chromatin interactions are important for gene regulation and cellular specialization. Emerging evidence suggests many-body spatial interactions play important roles in condensing super-enhancer regions into a cohesive transcriptional apparatus ...
Alan Perez-Rathke, Qiu Sun, Boshen Wang, Valentina Boeva, Zhifeng Shao, Jie Liang   +5 more
doaj   +1 more source

Transparent Perovskite Light‐Emitting Diodes with Conductive Oxide Top Electrodes

Advanced Materials, EarlyView.
Transparent perovskite light‐emitting diodes (TrPeLEDs) enable simultaneous display and transparency, expanding application possibilities. Using a metal oxide buffer layer and pulsed laser deposition, TrPeLEDs with diverse compositions and architectures are demonstrated.
Michele Forzatti, Sergio Martínez‐Saiz, Morena Cervino, Edoardo Stanzani, Sandra Jenatsch, Qingsen Zeng, Joo Sung Kim, Dong‐Hyeok Kim, Eojin Yoon, Tae‐Woo Lee, Daniel Tordera, Henk J. Bolink   +11 more
wiley   +1 more source

Impact of COVID-19 Pandemic-Related Restrictions for Inpatients with Aphasia and Associated Cognitive Dysfunction: Lessons Learned from Patient Detention

COVID
We describe two patients with a recent stroke or traumatic brain injury associated with aphasia and cognitive impairment who required detention (under the Mental Health Act) as well as some form of restraint during their inpatient rehabilitation. Each of
Edwin Eshun, Killian Welch, Hannah Britton, Victoria Mayer, Fay Morrice, Charlotte Ogilvie, Helen Page, Jessie Pridmore, Alasdair FitzGerald   +8 more
doaj   +1 more source

Miniature Soft Robot With Magnetically Reprogrammable Surgical Functions

Advanced Materials, EarlyView.
Miniature soft robots have great prospects to revolutionize minimally invasive treatments. Here we present a miniature soft robot, which can be reprogrammed to perform five surgical functionalities with six‐degrees‐of‐freedom motions. This soft robot can prospectively make minimally invasive surgery considerably safer and painless, and enable ...
Chelsea Shan Xian Ng, Yu Xuan Yeoh, Nicholas Yong Wei Foo, Keerthana Radhakrishnan, Guo Zhan Lum   +4 more
wiley   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

3D‐Printing Aided Rapid Prototyping of Pretensioned Tensegrity Structures for Robotic Applications

Advanced Robotics Research, EarlyView.
Printing, injection molding, and assembly (PMA) is a method for rapid prototyping mesoscale, topologically complex, and tensioned tensegrity structures. In combination with PMA method, two mold design strategies: modular mold and compact channel layout, enable efficiency and scalability for tensegrity fabrication.
Yi Sun, Jan Petrš, Omar Aloui, Dario Floreano   +3 more
wiley   +1 more source

Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease

Frontiers in Aging Neuroscience
Although impaired insulin signaling in the brain has been recognized as a key factor in the development and progression of Alzheimer’s disease (AD), the underlying mechanisms remain incompletely understood.
Faruk Hossen, Javier Hung, Hamza Odeh, Grace Y. Sun, James C. Lee   +4 more
doaj   +1 more source

Learning‐Based Soft Robotic Grasping: Recent Progress and Remaining Challenges

Advanced Robotics Research, EarlyView.
This review analyzes learning‐based soft robotic grasping from a pipeline‐oriented perspective, encompassing soft gripper design, multimodal sensing, and learning‐based planning and control. It surveys key neural network architectures and benchmark datasets and identifies critical challenges such as sim‐to‐real transfer, generalization, and continual ...
Arnab Majumder, Jelizaveta Konstantinova, Graham Deacon, Kaspar Althoefer   +3 more
wiley   +1 more source