Results 191 to 200 of about 83,367 (302)

Protecting CEACAM1 Expression Prevents Diet‐Induced Metabolic Dysfunction and Hepatic Fibrosis in Male Mice

Obesity, EarlyView.
ABSTRACT Objective High‐fat diet represses Ceacam1 transcription via a PPARα‐mediated mechanism to cause insulin resistance before inflammation develops. The current study investigated whether mutating PPRE‐RXRα in Ceacam1 promoter prevents diet‐induced metabolic abnormalities and hepatic fibrosis in male C57BL6/J mice.
Raziyeh Abdolahipour, Saja S. Khuder, William M. Philbrick, Agnes O. Portuphy, Getachew D. Belew, Hatem G. Fallouh, Harrison T. Muturi, Boyeon Kim, Jason K. Kim, Sonia M. Najjar   +9 more
wiley   +1 more source

Orbital metastasis from breast carcinoma: structured literature review and report of four cases. [PDF]

Front Ophthalmol (Lausanne)
Kim C, Bergman M, Fu R, Vargason C, Burnstine MA.   +4 more
europepmc   +1 more source

CHARGE Syndrome: What an Otolaryngologist Should Know—A Systematic Review and Meta‐Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To synthesize the prevalence of otolaryngologic manifestations in CHARGE syndrome (CS) to support otolaryngologists in delivering comprehensive management. Data Sources PubMed/MEDLINE, Embase, and Google Scholar were searched for English‐ and French‐language studies published from January 1980 through January 2025.
Camille Caron, Massil Badji, Camille Prigent, Alix Pincivy, Erika Mercier, Mathieu Bergeron   +5 more
wiley   +1 more source

Incidental [⁶⁸Ga]Ga-DOTATATE uptake in bone metastases of breast carcinoma in a patient with a secondary carcinoid tumor. [PDF]

EJNMMI Res
Kemle J, Pop SG, Sauter A, Pereira R, Nothhelfer T, Singer G, Leo C, Burger IA.   +7 more
europepmc   +1 more source

The role of tryptophan hydroxylase‐1 in metabolic dysfunction‐associated steatotic liver disease

Pediatric Investigation, EarlyView.
Silencing hepatic tryptophan hydroxylase 1 (TPH1) alleviated diet‐induced steatotic liver disease by reducing lipid accumulation, oxidative stress, inflammation, fibrosis, and hepatocyte apoptosis. These protective effects were mediated, at least in part, through restoration of Parkin‐dependent mitochondrial autophagy, identifying hepatic TPH1 as a ...
Shuangzhen Jia, Xiaolin Ye, Zhaoxia Wang, Jie Wu   +3 more
wiley   +1 more source

Tuoli Tounong decoction promotes lesion resolution in granulomatous lobular mastitis by remodeling a Caspase-8-associated PANoptosis-like cell death network. [PDF]

Front Immunol
Yuan Y, Zuo X, Gao X, Wang Y, Li X, Li Q, Chen Z, Shi X.   +7 more
europepmc   +1 more source

Liquiritigenin Ameliorates High‐Fat Diet‐Induced Hepatic Steatosis by Promoting Lipid Droplet Catabolism via PLIN2‐ATGL Regulation

Phytotherapy Research, EarlyView.
Liquiritigenin promotes expression of CGI‐58 and enhances lipolysis by down‐regulating expression of PLIN2, thereby facilitating the catabolism of larger‐sized lipid droplets and producing smaller‐sized lipid droplets, resulting in enhanced activity of lipophagy and ameliorated hepatic steatosis. ABSTRACT Metabolic‐associated fatty liver disease (MAFLD)
Zhuoya Xu, Jingmiao Chen, Hong Qin, Yansong Fu, Cunqi Lv, Zhipeng Wang, Xi Liu, Wenya Zheng   +7 more
wiley   +1 more source

Occult Pathology in the Contralateral Prophylactic Mastectomy Specimen Despite a Negative Contralateral MRI: A Single-Center Cohort Study. [PDF]

Cancers (Basel)
Yılmaz OC, Gündoğdu A, Aktaş M, Ertekin K, Tokoçin M, Gentile D, Sönmez Wetherilt C, Çelik L.   +7 more
europepmc   +1 more source

Oral Microalgae‐Laden Hydrogels Modulating the Intestinal Microbiota Metabolism for Acute Alcohol‐Induced Liver Injury Therapy

Small, EarlyView.
A food‐grade microalgae‐laden hydrogel (FMH) enables efficient in situ microalgae cultivation and serves as an oral therapeutic platform for acute alcohol‐induced liver injury. FMH improves alcohol tolerance, alleviates oxidative stress, inflammation, and lipid metabolic disorders, restores gut microbial homeostasis, and provides synergistic ...
Zhixin Hu, Hongtao Wu, Xuanqi Liu, Xinxu Huang, Linli Jiang, Lei Liu, Xiaojie Li, Yawen Yao, Fengzheng Gao, Kui Zeng, Jiajing Zhou   +10 more
wiley   +1 more source

Changes in the minor salivary glands and ductal carcinoma resulting from induction of oral carcinogenesis. [PDF]

J Mol Histol
Maia CR, de Oliveira RCE, da Silva VTC, Souza CC, de Oliveira VGN, Costa ABB, de Andrade Santos PP.   +6 more
europepmc   +1 more source