Results 201 to 210 of about 83,367 (302)

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

open access: yesSmall, EarlyView.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo   +15 more
wiley   +1 more source

Case report of invasive lobular carcinoma with pineal metastasis. [PDF]

open access: yesOxf Med Case Reports
Saito M   +10 more
europepmc   +1 more source

HSPE1 deficiency underlies the crosstalk between metabolic dysfunction‐associated steatotic liver disease and age‐related macular degeneration

open access: yesVIEW, EarlyView.
Rare‐earth ions act as multifunctional modifiers in perovskite solar cells by improving charge transport, suppressing oxygen vacancies, passivating defects, promoting grain growth, and enabling redox‐mediated stabilization. In addition, RE‐doped layers can expand spectral utilization through upconversion and downconversion, thereby enhancing light ...
Jiaqi Meng   +9 more
wiley   +1 more source

Comparison of Long‐Term Health‐Related Quality of Life After Mastectomy and Breast Conserving Therapy

open access: yesWorld Journal of Surgery, EarlyView.
Long‐term BREAST‐Q outcomes after breast‐conserving therapy (BCT) and mastectomy without reconstruction. Women treated with BCT reported higher psychosocial, sexual, and physical well‐being and greater satisfaction with their breasts than women treated with mastectomy.
Sanna Järvinen   +5 more
wiley   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue   +3 more
wiley   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong   +5 more
wiley   +1 more source

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