Results 41 to 50 of about 114,860,682 (209)

An Optimized Freeze‐Dry Multimodal Workflow for Sequential Micro‐CT Imaging, Histology, and Molecular Profiling: A Use Case in Human Liver Fibrosis

Advanced Science, EarlyView.
Optimized freeze‐drying and eosin staining deliver artifact‐free micro‐CT images of liver tissue at near‐histological detail, then hand the same specimen back for sectioning, staining, and sequencing. Fibrotic volume distinguishes normal liver from cirrhosis, while preserved RNA reveals inflammatory gene upregulation—one biopsy, three dimensions, and a
Kristijan Skok, Laura Činč Ćurić, Jernej Vajda, Silvia Schauer, Martin Wagner, Rudolf Stauber, Carolin Lackner, Karl Kashofer, Markus Plass, Giovanny Rodriguez Blanco, Ian R. Wanless, Uroš Maver, Katrin Panzitt, Boštjan Vihar   +13 more
wiley   +1 more source

Pure secretory carcinoma in situ: a case report and literature review

Diagnostic Pathology, 2019
Background Secretory breast carcinoma is an exceptionally rare type of breast carcinoma. Only 5 cases of pure secretory carcinoma in situ have been reported in English literature. Herein, we reported a rare case of pure secretory breast carcinoma in situ.
Ying Yang, Zhiyuan Wang, Guoqing Pan, Shumo Li, Yingying Wu, Liu Liu   +5 more
doaj   +1 more source

Complications and Clinical Outcomes Following Modified Endoscopic Denker's With Pyriform Aperture Preservation: A Prospective Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The modified endoscopic Denker's (MED) approach provides access to all maxillary sinus (MS) walls for resection of various MS and retromaxillary pathologies, but the anteromedial maxilla has historically been resected. This study determined complication rates and outcomes following MED with pyriform aperture (PA) preservation ...
Yasser Almansour, Lane Donaldson, Khaled Kashlan, Swapna Vemuri, Jun Jin, John R. Craig   +5 more
wiley   +1 more source

Lobular Carcinoma In Situ of the Breast

The Breast Journal, 1999
LCIS was first described in 1941 as a distinct pathologic entity by Foote and Stewart who called it a "rare form of mammary carcinoma." It is thought to represent a transitional intra-epithelial, or in situ, stage in the evolution of breast cancer from hyperplastic breast epithelium. With the wide application of mammography, its detection has increased
openaire   +2 more sources

Lobular Carcinoma in Situ with Atypical Mass Presentation: a Case Report [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2016
Lobular carcinoma in situ (LCIS) is associated with an increased risk of breast cancer and accounts for 1 to 2% of all breast cancers. LCIS diagnosis currently remains one of the major identifiable risk factors for subsequent breast cancer development ...
Luciana Graziano, Almir Galvão Vieira Bitencourt, Camila Souza Guatelli, Juliana Alves Souza, Cynthia Aparecida Bueno de Toledo Osório, Miriam Rosalina Brites Poli, Elvira Ferreira Marques   +6 more
doaj   +2 more sources

Value of Axillary Palpation and Ultrasound, and Axillary Recurrence in Male Breast Cancer: Results of the Registry Study

International Journal of Cancer, EarlyView.
ABSTRACT Clinical and sonographic examination of breasts and axillae is standard in breast cancer (BC) care. The aim of this study is to highlight the value of axillary ultrasound in identifying axillary recurrences in male BC, which is still little considered in the literature.
Monika Graeser, Susen Bothin, Oleg Gluz, Mathias Warm, Atanas Ignatov, Holm Eggemann   +5 more
wiley   +1 more source

Impact of Single‐Cell RNA Reference Selection for the Deconvolution of Breast Cancer Spatial Transcriptomics Datasets

International Journal of Cancer, EarlyView.
ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer, Scott J. Walker, Carsten O. Daub   +2 more
wiley   +1 more source

EXPRESSION OF b-HCG IN BREAST TUMORS

The Iraqi Journal of Medical Sciences, 2016
Background: Human chorionic gonadotropin (HCG) is a glycoprotein hormone, which consists of two polypeptide subunits (alpha and beta), produced by syncytial trophoblast cells of the placenta during pregnancy.
Rafal AR Al-Rawi, Faiza AZ Al-Rawi
doaj   +4 more sources

FGFR-1 amplification in metastatic lymph-nodal and haematogenous lobular breast carcinoma

Journal of Experimental & Clinical Cancer Research, 2012
Background Lobular breast carcinoma usually shows poor responsiveness to chemotherapies and often lacks targeted therapies. Since FGFR1 expression has been shown to play pivotal roles in primary breast cancer tumorigenesis, we sought to analyze the ...
Brunello Eleonora, Brunelli Matteo, Bogina Giuseppe, Caliò Anna, Manfrin Erminia, Nottegar Alessia, Vergine Marco, Molino Annamaria, Bria Emilio, Massari Francesco, Tortora Giampaolo, Cingarlini Sara, Pedron Serena, Chilosi Marco, Zamboni Giuseppe, Miller Keith, Martignoni Guido, Bonetti Franco   +17 more
doaj   +1 more source

Apocrine carcinoma of the breast: Review

Forum of Clinical Oncology, 2023
Apocrine carcinoma of the breast is a rare subtype of breast carcinoma, which only presents as 4% among patients with breast cancer. The percentage varies based on the diagnostic criteria used by each institution to classify apocrine carcinoma.
Yang Chieh, Wang Irene, Yen Yun
doaj   +1 more source