Results 91 to 100 of about 9,603,459 (362)
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
11-S: The Overflows of The New Global Empire
Revista de Culturas y Literaturas Comparadas, 2015 Undoubtedly, 9/11 represents a moment of inflection in the history of the United States. With the exception of the invasion of the air space back in time in faraway Pearl Harbour, the United States had never been the object of attacks in its territory. 9/
Miriam Carballo
doaj
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Exchange on Nick Onuf’s ‘Metaphoricizing Modernity,’ Part III–Reconfiguration of Modernity and/as Metaphor(s) [PDF]
Contexto InternacionalIn this Dossier, four scholars reflect on Nicholas Onuf’s leading article, ‘Metaphoricizing modernity’, (re)engaging with – and celebrating – more broadly Onuf’s groundbreaking work from different places, perspectives, and angles.
Michael Marks, Nicholas Onuf
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Local DCPOs, Local CPOs and Local Completions
Electronic Notes in Theoretical Computer Science, 1999 AbstractWe use a subfamily of the Scott-closed sets of a poset to form a local completion of the poset. This is simultaneously a topological analogue of the ideal completion of a poset and a generalization of the sobrification of a topological space. After we show that our construction is the object level of a left adjoint to the forgetful functor from
openaire +1 more source
Sleep Medicine Reviews, 2019 The historic sleep regulatory paradigm invokes "top-down" imposition of sleep on the brain by sleep regulatory circuits. While remaining conceptually useful, many sleep phenomena are difficult to explain using that paradigm, including, unilateral sleep, sleep-walking, and poor performance after sleep deprivation.
Krueger, James M +3 more
openaire +3 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
From local explanations to global understanding with explainable AI for trees
Nature Machine Intelligence, 2020 Scott M. Lundberg +9 more
semanticscholar +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source