Results 161 to 170 of about 23,275,318 (397)
STUDIES ON GANGRENE FOLLOWING COLD INJURY. V. THE USE OF FLUORESCEIN AS AN INDICATOR OF LOCAL BLOOD FLOW: FLUORESCEIN TESTS IN EXPERIMENTAL FROSTBITE 1 [PDF]
J. M. Crismon, Frederick A. Fuhrman
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This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
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In this interview Dben zen discusses a number of local home remediesThis collection presents forty-nine audio files including: several folk song genres; folktales and; local history from the Sman shad Valley of Sde dge CountyWorld Oral Literature ...
Zla ba sgrol ma
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This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
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Local Massage for Local Neurasthenia [PDF]
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Proceedings of Local Branches of the Society of American Bacteriologists, New Jersey and Connecticut Valley Branches [PDF]
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The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
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ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
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Local Trade:Supporting Local Economic Resilience in the Digital Age [PDF]
This paper discusses the importance of economic resilience in times of financial turmoil and presents the preliminary results of a study on a new approach to supporting regional and local economies by incentivising locally beneficial consuming and ...
Balis, Gerasimos
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A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
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