Results 81 to 90 of about 4,020,968 (269)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Irish local and artisan foods: Multiples make space!
Cogent Business & Management, 2017 Consumers are increasingly discerning about food choices. This research explores the attitudes of Irish consumers to local and artisan food products, and, in particular, if they would consider the supermarket environment as a location of choice for the ...
Michelle Dunne, Angela Wright
doaj +1 more source
Local DCPOs, Local CPOs and Local Completions
Electronic Notes in Theoretical Computer Science, 1999 AbstractWe use a subfamily of the Scott-closed sets of a poset to form a local completion of the poset. This is simultaneously a topological analogue of the ideal completion of a poset and a generalization of the sobrification of a topological space. After we show that our construction is the object level of a left adjoint to the forgetful functor from
openaire +1 more source
Sleep Medicine Reviews, 2019 The historic sleep regulatory paradigm invokes "top-down" imposition of sleep on the brain by sleep regulatory circuits. While remaining conceptually useful, many sleep phenomena are difficult to explain using that paradigm, including, unilateral sleep, sleep-walking, and poor performance after sleep deprivation.
Krueger, James M +3 more
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Global Bauls, Local Bauls: Community, Violence and Everyday Life
Glocalism: Journal of Culture, Politics and Innovation, 2020 The enormous power of globalization influences not only the local communities but also the pattern of everyday life of the individuals who belong to those communities. The global often involves violence in its course to interact with the local.
Arnav Debnath
doaj
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Local Homology and Local Cohomology
, 2004 Let $(R, {\frak m})$ be a local ring, $I$ a proper ideal of $R$ and $M$ a finitely generated $R$-module of dimension $d$. We discuss the local homology modules of $H^d_I(M)$. When $M$ is Cohen-Macaulay, it is proved that $H^d_{\frak m}(M)$ is co-Cohen-Macaulay of N.dimension $d$ and $H^{\underline{x}}_d(H^d_{\frak m}(M))\cong\hat{M}$ where $\underline ...
openaire +3 more sources