Results 81 to 90 of about 608,751 (263)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Local action group as driving force for the development of local agrifood systems

open access: yesRURAL DEVELOPMENT 2019, 2013
The purpose of this paper is to explore the possibility to activate Local Agrifood Systems in the LEADER areas. TheLASshave the aim to activate and manage alternative, local and short food chain, involving communities, protecting and implementing the quality and the environment, creatingvaluefor local andmarginal agriculture, therefore they can provide
G. Ferrazzi, S. Corsi, A. Tosini
openaire   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Regional Development and Climate Change Adaptation: A Study of the Role of Legitimacy

open access: yesEuropean Countryside, 2016
This paper presents results from a study of Czech Local Action Groups (LAGs), focusing on gaining knowledge about their internally perceived legitimacy and their potential role in local adaptation to climate change.
Thorstensen Erik   +4 more
doaj   +1 more source

Local action groups and the LEADER co-financing of rural development projects in Slovenia

open access: yesAgricultural Economics (AGRICECON), 2014
The influence of a formal and informal system of the Local Action Group (LAG) board's performance on the perception of its members is analysed in association with the suitability of the rural development projects for the LEADER funds co-financing.
Alenka VOLK, Štefan BOJNEC
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The role of local elected officials in the making of LEADER local action groups in the Czech Republic

open access: yesWieś i Rolnictwo, 2012
Local elected officials in practice exercise political leadership by their involvement in partnerships and their status on the local co-operation scene.
Marie-Claude Maurel
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

INTEGRATING ARTIFICIAL INTELLIGENCE INTO LOCAL DEVELOPMENT: THE POTENTIAL OF AI TO IMPROVE THE MANAGEMENT AND EFFECTIVENESS OF LOCAL ACTION GROUPS (LAGS)

open access: yesJournal of Bio-Based Marketing
This publication explores the potential of artificial intelligence (AI) to transform the activities of Local Action Groups (LAGs). Through qualitative and conceptual analysis based on contemporary scientific literature and good practices from Europe and ...
Kaloyan Stoychev
doaj  

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