Results 61 to 70 of about 625,401 (305)
Quaestiones Geographicae, 2020 Social innovation entered the academic discourse several decades ago and has since been seen as a way of tackling existing problems in various contexts. Although an extensive body of research has been conducted into the role of social innovation in urban
Novikova Marina +2 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Products of Locally Compact Groups with Zero and Their Actions
Canadian Journal of Mathematics, 1971 In [4], Hofmann defines a locally compact group with zero as a Hausdorff locally compact topological semigroup, S, with a non-isolated point, 0, such that G = S — {0} is a group. He shows there that 0 is indeed a zero for 5, G is a locally compact topological group, and the identity of G is the identity of S. The author has investigated actions of such
openaire +3 more sources
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Beyond PRA: experiments in facilitating local action in water management
, 2005 As a tool both for research and for structuring community-level interaction, Participatory Rural Appraisal (PRA) is now well embedded in development practice.
Sekhar Nandi, Snehangshu, Schaap, Wouter
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
, 2005 Objective: To develop and refine a complex intervention for diabetes support and education in minority ethnic groups, delivered through bilingual health advocates.
Greenhalgh, T. +6 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
CAPACITY BUILDING OF RURAL AREAS IN SERBIA THROUGH FORMING LOCAL ACTION GROUPS
Ekonomika Poljoprivrede (1979), 2011 In great part of its rural areas, Serbia has all prerequisites for promotion and successful implementation of the concept of Local action groups and integrated rural development: richness of diversity in rural areas, signifcant natural resources ...
Vesna Paraušić +2 more
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LOCAL ACTION GROUPS - THE EUROPEAN INTEGRATION CATALYST FOR THE ROMANIAN RURAL AREA [PDF]
Annals of the University of Oradea: Economic Science, 2011 Romania has the highest share of European Union rural areas (44.9% in 2009), which generates and maintains a long series of regional disparities. Because of these disparities, the economy faces a number of elements that undermine the quality of human and
Mosora Liviu - Cosmin, Ailenei Dorel
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