Results 41 to 50 of about 14,091,733 (230)

Alike in diversity? Local action groups in nine European countries

, 2022
Local Action Groups (LAGs) are seen as an integral part in the development of rural economies across the EU. They are a strong network of interaction between the local state and society.
Teles, Filipeeditor, Lysek, Jakubeditor, Krukowska, Joanna, Heinelt, Huberteditor, Silva, Patriciaeditor, Navarro, Carmen, Copus, ColinUGent8020028883139787087871109B7BC7D0-65E7-11E8-B53A-AFC811A95AF2, Egner, Björneditor, Jones, Alistair, Lysek, Jakub   +9 more
core  

Are LEADER principles achieved in Local Action Groups? A systematic assessment of local representatives' perception [PDF]

Eastern Journal of European Studies
Rural development is often hindered by the lack of human and social capital. The LEADER program is one of the European Union's financial instruments destined to improve the rural areas governance by introducing a set of institutional changes including ...
Ana-Maria Opria, Ema Corodescu-Roșca, Lucian Rosu   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Breaking down barriers in building teacher competence [PDF]

, 2012
Teachers may well be made, not born, and appointments to academic positions are often made without regard to the appointee’s prior experience or competence in teaching.
Bruce Ferguson, Pip, Bruce Fergusson, Pip   +1 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Lack of Attention Given by Neoendogenous Rural Development Practice to Areas Highly Affected by Depopulation. The Case of Andalusia (Spain) in 2015–2020 Period

European Countryside, 2021
How are the problems of depopulation being faced by the Local Action Groups (LAGs) and the LEADER approach? What kinds of proposals are being pointed out to tackle young people’s exodus, the economic depression, the physical and virtual distances, and ...
Navarro-Valverde Francisco, Cejudo-García Eugenio, Pérez José Antonio Cañete   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source