Results 91 to 100 of about 482,757 (314)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

A Few Stickleback Suffice for the Transport of Alleles to New Lakes

open access: yesG3: Genes, Genomes, Genetics, 2020
Threespine stickleback populations provide a striking example of local adaptation to divergent habitats in populations that are connected by recurrent gene flow. These small fish occur in marine and freshwater habitats throughout the Northern Hemisphere,
Jared Galloway   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Indigenous women's preference for climate change adaptation and aquaculture development to build capacity in the Northern Territory [PDF]

open access: yes, 2013
Research was carried out on South Goulburn Island, Northern Territory, to improve understandings of local, Indigenous people’s dependency on marine resources, and of their perspectives on climate change, and aquaculture as a means towards adapting to ...
Lisa Petheram   +2 more
core  

Locally led adaptation: drivers for appropriate grassroots initiatives

open access: yes, 2021
Adapting to the impacts of climate change is one of the most urgent priorities of our time. Given that the impacts of climate change are experienced at local scales, it makes sense that adaptation should occur locally, and yet, despite this, locals often
Fernando, Nishara   +6 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Adaptation to climate in widespread eucalypt species [PDF]

open access: yes, 2013
The long term success of revegetation efforts will depend upon the planted species’ resilience to climate change. Many widespread species grow across a range of climatic conditions and, thus, may possess adaptations that could be utilised to improve ...
Suzanne Prober   +2 more
core  

Transforming Local Climate Adaptation Organization : Barriers and Progress in 13 Swedish Municipalities

open access: yes, 2021
Local strategies and policies are key in climate adaptation, although research shows significant barriers to progress. Sweden, often seen as progressive in climate change issues, has struggled in adopting a sufficient local climate adaptation ...
Kristianssen, Ann-Catrin,   +5 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Valuing adaptation under rapid change [PDF]

open access: yes, 2013
The methods used to plan adaptation to climate change have been heavily influenced by scientific narratives of gradual change and economic narratives of marginal adjustments to that change.
Celeste Young   +2 more
core  

Home - About - Disclaimer - Privacy