Results 91 to 100 of about 482,757 (314)
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
A Few Stickleback Suffice for the Transport of Alleles to New Lakes
Threespine stickleback populations provide a striking example of local adaptation to divergent habitats in populations that are connected by recurrent gene flow. These small fish occur in marine and freshwater habitats throughout the Northern Hemisphere,
Jared Galloway +2 more
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Indigenous women's preference for climate change adaptation and aquaculture development to build capacity in the Northern Territory [PDF]
Research was carried out on South Goulburn Island, Northern Territory, to improve understandings of local, Indigenous people’s dependency on marine resources, and of their perspectives on climate change, and aquaculture as a means towards adapting to ...
Lisa Petheram +2 more
core
Locally led adaptation: drivers for appropriate grassroots initiatives
Adapting to the impacts of climate change is one of the most urgent priorities of our time. Given that the impacts of climate change are experienced at local scales, it makes sense that adaptation should occur locally, and yet, despite this, locals often
Fernando, Nishara +6 more
core +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Adaptation to climate in widespread eucalypt species [PDF]
The long term success of revegetation efforts will depend upon the planted species’ resilience to climate change. Many widespread species grow across a range of climatic conditions and, thus, may possess adaptations that could be utilised to improve ...
Suzanne Prober +2 more
core
Local strategies and policies are key in climate adaptation, although research shows significant barriers to progress. Sweden, often seen as progressive in climate change issues, has struggled in adopting a sufficient local climate adaptation ...
Kristianssen, Ann-Catrin, +5 more
core +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Valuing adaptation under rapid change [PDF]
The methods used to plan adaptation to climate change have been heavily influenced by scientific narratives of gradual change and economic narratives of marginal adjustments to that change.
Celeste Young +2 more
core

