Results 101 to 110 of about 482,757 (314)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Network governance and climate change adaptation: collaborative responses to the Queensland floods [PDF]
, 2013 This research examines ways to build adaptive capacity to climate change, through a case study of organisations that participated in the response to Queensland’s major flood disaster in Queensland in 2010/11.
Kym Patison, Julie Mann, Susan Kinnear
core
Gendering local climate adaptation
, 2013 Empirical evidence suggests that climate change will hit women disproportionately hard. Lack of political power, small economic resources, gender-bound patterns in the division of labour, entrenched cultural patterns and possibly biological differences ...
Edvardsson Björnberg, Karin, +1 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Climate change adaptation in the boardroom [PDF]
, 2013 Climate adaptation is recognised by many of the world’s largest businesses as a global risk and one that requires critical attention. The World Economic Forum’s 2013 Global Risks Perception Survey, identified the ‘failure of climate change adaptation and
Mark Baker-Jones +2 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Joining the dots: hydrology, freshwater ecosystem values and adaptation options [PDF]
, 2013 The objective of this research was to investigate and test the necessary steps in developing an adaptation planning framework for freshwater biodiversity.
Leon Barmuta, Peter Davies, Anne Watson
core
Symbiotic adaptation in local strains of red clover and nodule bacteria
, 1952 A study has been made of the response of a number of local strains of British and Swedish red clover in symbiosis with nodule bacteria isolated from the localities from which the plant strains were obtained.
Nutman, P. S., Read, M. P.
core +1 more source
FACETS, 2017 The fungus that causes bat white-nose syndrome (WNS) recently leaped from eastern North America to the Pacific Coast. The pathogen’s spread is associated with the genetic population structure of a host (Myotis lucifugus).
Christina M. Davy +13 more
doaj +1 more source