Results 121 to 130 of about 482,757 (314)

Reconceptualising adaptation to climate change as part of pathways of change and response [PDF]

, 2014
The need to adapt to climate change is now widely recognised as evidence of its impacts on social and natural systems grows and greenhouse gas emissions continue unabated.
Park, Sarah, Park, S.E., Wise, RM, Fazey, I, Campbell, Bruce M., Park, S. E., Campbell, Bruce Morgan, Park, SE, Archer Van Garderen, ERM, Smith, M. Stafford, Eakin, H.C., Stafford Smith, M.D., Archer Van Garderen, E. R. M., Campbell, B., Wise, R.M., Archer Van Garderen, E.R.M., Van Garderen, E.R.M. Archer, Eakin, H. C., Fazey, I., Stafford Smith, M., Wise, R. M.   +20 more
core   +1 more source

Peripheral Isolates as Sources of Adaptive Diversity under Climate Change

Frontiers in Ecology and Evolution, 2017
As climate change progresses, there is increasing focus on the possibility of using targeted gene flow (TGF, the movement of pre-adapted individuals into declining populations) as a management tool.
Stewart L. Macdonald, Stewart L. Macdonald, John Llewelyn, John Llewelyn, Craig Moritz, Ben L. Phillips, Ben L. Phillips   +6 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Adaptation at scale in semi-arid regions [PDF]

, 2015
French version available in IDRC Digital Library: Adaptation à différentes échelles dans les régions semi-aridesWorking with stakeholders from Botswana, India, Ethiopia, Ghana, Kenya, Mali, Namibia, and Uganda, the Adaptation at Scale in Semi-Arid ...
IDRC. Collaborative Adaptation Research Initiative in Africa and Asia (CARIAA)
core  

Climate change adaptation in mountains: How to close the gap between policies and local realities?

, 2022
People living in mountain regions are among those most exposed to climate change risks. Despite major efforts to promote adaptation, gaps between policies and local responses persist and limit effective pathways toward more resilient mountain communities.
McDowell, Graham, Thibault, Marlène, Portner, Brigitte, Budoyan, Nona, Dupuits, Emilie, Kinusu, Kevin, Fellendorf, Ansgar, Mathez-Stiefel, Sarah-Lan   +7 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Community-based Adaptation: Lessons from the Development Marketplace 2009 on Adaptation to Climate Change [PDF]

The Development Marketplace 2009 focused on adaptation to climate change. This paper identifies lessons from the Marketplace and assesses their implications for adaptation support.
Habiba Gitay, Radhika Prabhu, Rasmus Heltberg   +2 more
core  

Climate change adaptation for Australian minerals industry professionals [PDF]

, 2013
Extreme weather events in Australia over recent years have highlighted the costs for Australian mining and mineral processing operations of being under-prepared for adapting to climate risk.
Leah Mason, Mason, LM, Damien Giurco, Giurco, D   +3 more
core  

Adaptive Sampling for Fingerprinting Localization

2025 IEEE 102nd Vehicular Technology Conference (VTC2025-Fall)
Peer ...
Al-Tous Hanan, Tirkkonen Olav, Li Xinze
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source