Results 41 to 50 of about 8,834,903 (313)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Os presidentes de Câmara italianos: Uma revolução de compromisso

Revista Crítica de Ciências Sociais, 2007
During the ‘90s in Italy several radical reforms took place: an unprecedented conjunction of political, electoral, administrative, institutional and constitutional transformations, which changed the shape of the Italian politics.
Silvia Bolgherini
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The Classification Plan for Local Administration: Portuguese Archives and the Knowledge Organization in Practice

, 2020
This paper presents recent developments in Portuguese local archives’ classification policies. Following several professional workgroups and reinforced with a political mandate, local administration archives are putting in practice a new knowledge ...
Luís Corujo, Carlos Guardado da Silva, Corujo, Luís, 1976-, Silva, Carlos Guardado da, 1971-, Revez, Jorge, 1980-, Jorge Revez   +5 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Effects, Challenges, and Preconditions for Implementing Direct Health Facility Financing and the Prime Vendor Model in Low-Resource Settings: The Experience from Tanzania

Health Systems & Reform
Primary health care (PHC), while critical to achieving universal health coverage, remains underfunded and often delivers poor-quality care. In response, Tanzania introduced two innovative and complementary reforms—Direct Health Facility Financing (DHFF ...
Peter Binyaruka, Douglas Ndeki, Raymond Kiwesa, Regina Joseph, Bakari Salum   +4 more
doaj   +1 more source

Guidelines on parking management : sustainable mobility [PDF]

, 2023
This document is one in a series of documents on Sustainable Mobility and includes other important subjects – Walkability and Accessibility, Shared Transport, Last Mile Transportation and EV Changeover, previously issued by the Local Councils ...
Zammit, Antoine, Local Councils' Association   +1 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Research on online public opinion dissemination and emergency countermeasures of food safety in universities—take the rat head and duck neck incident in China as an example

Frontiers in Public Health
In recent years, food safety accidents have occurred frequently in colleges and universities, and students are prone to emotional resonance with food safety.
Jinsi Liu, Jinsi Liu, Su Wang, Su Wang, Zhihua Wang, Shixiang Chen, Shixiang Chen   +6 more
doaj   +1 more source