Results 51 to 60 of about 48,373 (308)

Sobre la Administración competente para sancionar a los funcionarios de Administración local con habilitación de carácter nacional interinos

Revista Vasca de Administración Pública, 2021
This paper analyses the legal legitimacy of articles 61 and 62 of the Royal Decree 128/2018, of March 16, regulating the legal regime of Local Administrations¿ civil servants with a national habilitation.
Antonio Ezquerra Huerva
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Personalized extended government for local public administrations

, 2015
This paper discusses the enterprise organization environment and reports our experience and lessons learned in developing an extension of the traditional virtual enterprise model, we named personalized extended government (PEG) model.
Biancalana C., Sansonetti G., Micarelli A.   +2 more
core  

Hyper-reality and statebuilding: Baudrillard and the unwillingness of international administrations to cede control

, 2011
A characteristic feature of many contemporary international administrations of post-conflict territories has been the reluctance of the administrating body to rescind its competences.
Hehir, A.
core   +1 more source

The responsibility of officials of local administrations for violations in the sphere of land relations.

Теорія і практика правознавства, 2016
Problem Setting. The article studies the question of responsibility of officials of local administrations for violations in the sphere of land relations. The analysis of scientific papers in the study area, considered issues related to the classification
А. С. Самородов
doaj   +1 more source

Dynamics of Everyday Life within Municipal Administrations in Francophone and Anglophone Africa

Africa Spectrum, 2020
Decentralisation in sub-Saharan Africa promises to build responsive institutions, hold officials to account and promote popular participation. Still, existent studies ignore the everyday interface between decentralised structures and citizens, as well as
Matthew Sabbi, Lamine Doumbia, Dieter Neubert   +2 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Perceived life stressors and societal risk judgments of rural residents: Moderate effects of public satisfaction with local administrations

, 2011
The purpose of present study was to explore the rela-tionship between perceived life stressors and judgment to societal problems, and the moderating role of public satisfaction with local administrations.
Zhou ZH(周智红), Wang EP(王二平)
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source