Results 71 to 80 of about 289,917 (314)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Local administration of platelets [PDF]

open access: yesBone Marrow Transplantation, 1997
G, Kusminsky, M, Zylberman
openaire   +2 more sources

Should local public employment services be merged with the local social benefit administrations? [PDF]

open access: yes, 2011
The German Federal government has allowed some regions (Approved Local Providers) to be solely responsible for the care of long-term unemployed. The remaining regions had to form Joint Local Agencies, where the local social benefit administrations work ...
Holzner, Christian, Munz, Sonja
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Features of in the district administrations in the cities (the aspects of decentralization of state power)

open access: yesAspekti Publìčnogo Upravlìnnâ, 2015
The article analyses the modern activity of district administrations in the cities, their legal status and the status of the chief of administration, his orders and powers, status of the meetings of administration as collegiate body, form and legal ...
Y. B. Yedynak
doaj  

FISCAL COMPETITION AND PUBLIC EDUCATION IN REGIONS [PDF]

open access: yes
We explore an economy with two regions and independent local administrations. Local governments collect taxes to finance public education, but once educated agents can choose to migrate to the other region.
Alexandra Rillaers   +2 more
core  

The Development of the European Administration: Fundamental Concepts and Approaches [PDF]

open access: yes, 2004
The study approaches in an unitary manner, the fundamental concepts of the theoretical and practical accomplishment of an European public administration: the European Administrative Space, the convergence and the administrative dynamics and the ...
Matei, Ani.
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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