Results 71 to 80 of about 48,373 (308)

Fiscal autonomy in local administrations: A review of Turkish case

, 2019
Mahalli idareleri idari ve mali yönden güçlendirmek, varoluş amaçlarına uygun yapılandırmak ve modern kamu yönetimi anlayışının getirdiği saydamlık, hesap verilebilirlik, katılımcılık gibi değerler çerçevesinde çalıştırabilmek için çeşitli reformlar ...
Tümer, Duygu
core  

Features of in the district administrations in the cities (the aspects of decentralization of state power)

Aspekti Publìčnogo Upravlìnnâ, 2015
The article analyses the modern activity of district administrations in the cities, their legal status and the status of the chief of administration, his orders and powers, status of the meetings of administration as collegiate body, form and legal ...
Y. B. Yedynak
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Education and Training Needs in the Field of Local Development in the Lower Danube Macro Region [PDF]

The present paper is the result of an effort made by the authors to explore the needs of education and training in the field of local development, according to the situation in Romanian and Bulgarian Danube bordering regions, aiming at designing joint ...
Nicola Yankov, Alina Elena Balalia, Laurenţiu Tăchiciu   +2 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The models proposed for local administrations after 1980 in Turkey

, 2007
Yerel yönetimlerin ülkemiz yönetim yapısı içinde yer alması neredeyse yüz elli yıllık bir geçmişe sahiptir. Bu geçen zaman zarfında Yerel yönetimler tarihsel gelişim süreci içerisinde her dönemde değişik sorunlarla karşı karşıya kalmıştır.
Güçlü, Serkan
core  

Les administrations publiques locales dans le modèle "Administrations"

, 1980
Local government administrations in the «Administrations» model by F. Péronnet. France's local government administrations («Administrations publiques locales» or «Apul») comprise an aggregate of administrations of territorial competence and essentially ...
Péronnet, François
core   +1 more source

Editorial

Commonwealth Journal of Local Governance, 2012
The authors in this issue highlight crucial issues facing Commonwealth local governments today − ensuring national influence, maximising revenue generation, encouraging probity in staffing appointments, or dealing with problems of social exclusion and ...
Alison Brown
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source