Results 91 to 100 of about 289,917 (314)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Interaction and activity coordination of territorial customs bodies of the State fiscal service of Ukraine with local state administrations and local self-government bodies

Проблеми Законності, 2016
This article is devoted to problematic aspects of the interaction and activity coordination of territorial customs bodies of the State Fiscal Service (SFS) of Ukraine, with local state administrations and local self-government bodies.
Олексій Павлович Федотов
doaj   +1 more source

Knowledge Management for Public Administrations: Technical Realizations of an Enterprise Attention Management System [PDF]

, 2014
The improvement of governments’ efficiency has gained great importance and validity especially in the current times of economic downturn. E-Government constitutes the most contemporary techno-managerial proposition in the track of possible interventions.
Ntioudis, Spyridon, Samiotis, Konstantinos, Stojanovic, Nenad   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Systemic Or Incremental Path Of Reform? The Modernization Of The Judicial System In Italy

International Journal for Court Administration, 2013
The paper presents the first results of the monitoring of the national program "Diffusion of best practices within the Italian judicial offices". The program represents the first large scale attempt at modernization of the judicial offices and focuses on
Giancarlo Vecchi
doaj   +1 more source

How Civil Society Organizations Works Politically to Promote Pro-Poor Policies in Decentralized Indonesian Cities [PDF]

, 2011
This paper examines how civil society organizations (CSOs) have taken advantage of the increased opportunities created by decentralization to influence the role and functions of local administrations in urban areas of Indonesia.
Alam Surya Putra, Erman Rahman, Laurel MacLaren   +2 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

DECENTRALIZATION OF POWER UNDER CONDITIONS OF WAR: CHALLENGES FOR DEMOCRATIC LOCAL SELF-GOVERNMENT ON THE EXAMPLE OF KHARKIV REGION

Вісник Харківського національного університету імені В. Н. Каразіна: Серія "Питання політології"
The article analyzes impact of a full-scale war on the implementation of the decentralization reform. The decentralization reform, which began in 2014, was initially implemented against the backdrop of the Russian-Ukrainian war, but during 2022-2024 the ...
Anton Avksentiev
doaj   +1 more source

Organising supply chains of organic products for Italian school meals - The case of the province and of the city of Piacenza [PDF]

, 2009
The paper is part of the proceedings of an iPOPY seminar. The authors describe, how supply chains of organic school food might be organised in a sustainable way in order to serve high quality food to pupils.
Bocchi, Stefano, Noelting, Benjamin, Sarti, Valerio, Spigarolo, Roberto   +3 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source