Results 111 to 120 of about 5,960,966 (303)
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Education and Training Needs in the Field of Local Development in the Lower Danube Macro Region [PDF]
The present paper is the result of an effort made by the authors to explore the needs of education and training in the field of local development, according to the situation in Romanian and Bulgarian Danube bordering regions, aiming at designing joint ...
Nicola Yankov +2 more
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Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Evaluation of the Internal Auditing in Local Administrations: The Case of Turkey
, 2015 Internal auditing which is now being implemented in local administrations after the adoption of the Law No. 5018 on Public Financial Management and Control is a practice that would ensure econornical, effective, influential and quality service by the ...
Bilge, Semih, Daskaya, Nurten
core +2 more sources
AN EXAMINATION ON LOCAL PARTICIPATION WITH REGARD TO DEMOCRATISATION OF LOCAL ADMINISTRATIONS
, 2018 Yerel yönetimler, yerelde halkın ortak ihtiyaçlarını karşılayan kurumlardır. Yerel yönetimler, yerelde halkın kararalma süreçlerine katılımını sağlayabilmesi bakımından demokrasi ile ilişkilendirilmektedir.
Yaman, Murat, Küçükşen, Murat
core +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
The Elaboration Stages of Local Development Strategies
Revista Transilvană de Ştiinţe Administrative, 2003 This article - “The Elaboration Stages of Local Development Strategies” - aims to present a topic of current interest for Romanian local public administrations.
Márton BALOGH
doaj
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
The models proposed for local administrations after 1980 in Turkey
, 2007 Yerel yönetimlerin ülkemiz yönetim yapısı içinde yer alması neredeyse yüz elli yıllık bir geçmişe sahiptir. Bu geçen zaman zarfında Yerel yönetimler tarihsel gelişim süreci içerisinde her dönemde değişik sorunlarla karşı karşıya kalmıştır.
Güçlü, Serkan
core