Results 111 to 120 of about 48,373 (308)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Should local public employment services be merged with the local social benefit administrations? [PDF]

, 2011
The German Federal government has allowed some regions (Approved Local Providers) to be solely responsible for the care of long-term unemployed. The remaining regions had to form Joint Local Agencies, where the local social benefit administrations work ...
Munz, Sonja, Holzner, Christian
core  

BUILDING COMPETENCIES FOR MANAGING VIRTUAL TEAMS IN LOCAL PUBLIC ADMINISTRATIONS: CHALLENGES IN THE AGE OF GLOBAL DIGITALIZATION

Baltic Journal of Economic Studies
Objectives. The present article aims to examine the difficulties faced by local governments during their digital transitions, highlighting the urgent need to improve higher education programmes focused on public administration and related fields in ...
Silviа Beloeva, Nataliya Venelinova, Mariana Petrova   +2 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Functionality Problem of Special Provincial Administrations in The Ottoman and Turkey Local Government Tradition

, 2019
İl özel idarelerinin Osmanlı ve Türkiye’nin yerel yönetim geleneği içindeki işlevi statik bir seyir izlememektedir. Yerel yönetim yapısında meydana gelen değişimler, il özel idarelerinin dalgalı bir şekilde gelişmesine neden olmuştur.
Eyidiker, Uğur
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Factors influencing e-disclosure in local public administrations

We study the determinants of voluntary Internet financial reporting (e-disclosure) by local public administrations. We present hypotheses regarding the relationship between e-disclosure and city size, the issuing of municipal bonds, financial features ...
Pilar Portillo-Tarragona, Carlos Serrano-Cinca, Mar Rueda-Tom�s   +2 more
core  

Thorns in the side: Strategies of populist parties against local public administrations

The success of populist parties in national elections puts pressure on political leaders and their administrations, both at the central and sub‐national levels.
Drapalova, Eliska
core   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Local potentials for achieving sustainable development goals: qualitative evidence from local governments in Türkiye [PDF]

Although academia occasionally emphasises prioritising the local dimension in achieving the Sustainable Development Goals (SDGs), the potential of local governments to contribute to SDGs accomplishment remains a relatively unexplored area within academic
Gocoglu, Volkan, Gocoglu, Ipek Didem
core   +1 more source