Results 101 to 110 of about 496,747 (294)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Table Discussion Notes - Harmonizing Education for Local Concerns with Global Issues [PDF]

, 2016
Notes from table discussion on the topic of harmonizing education for local concerns with global issues. The scope of discussion included curriculum, pedagogy, extracurricular opportunities for students, and faculty development.
Portland State University
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Table Discussion Final Summary - Harmonizing Education for Local Concerns with Global Issues [PDF]

, 2016
Final summary of the table discussion on the topic of harmonizing education for local concerns with global issues. The scope of discussion included curriculum, pedagogy, extracurricular opportunities for students, and faculty development. After exploring
Portland State University
core   +1 more source

FBCCNet: a Bayesian perspective of federated learning with crowdsourced annotations on client side

Complex & Intelligent Systems
Federated learning has emerged as a promising privacy preserving distributed learning framework, enabling participating clients to collaboratively train a shared global model without exposing their local data.
Hangyu Zhu, Xilu Wang, Yaochu Jin
doaj   +1 more source

Facteur 4 en Nord-Pas de Calais : impacts socio-économiques

Développement Durable et Territoires, 2011
Cutting the greenhouse gas emissions by four by 2050 will have major consequences on local economies, households and policies. This objective is global, however, consequences will have to be faced and dealt with locally.
Anne-Sophie Stevance, Nicolas Houdant, Antoine Bonduelle   +2 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Negotiating local and global: Developing Social Science research ethics policy in a Central Asian context

Research Ethics Review
This paper addresses the issue of how local and global norms and requirements are negotiated in the early stages of development of Social Science research ethics policy in a Global South context.
Roza Sagitova, Zarena Syrgak kyzy, Lynne Parmenter   +2 more
doaj   +1 more source

Asian Drug Import, Local Production, and Regulatory Capacity in Tanzania, 1970–2005

Nordic Journal of African Studies
By the mid-2000s, the contribution of Tanzania’s pharmaceutical industry to local drug circulation was low compared to imports, with the latter mostly coming from India.
Peter Mangesho, Christoph Gradmann
doaj   +1 more source