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Local Anesthetics [PDF]

open access: greenJournal of Industrial & Engineering Chemistry, 1922
n ...
Henry Gilman
openalex   +5 more sources

The thermodynamics of general and local anesthesia [PDF]

open access: yesBiophys. J. 2014, 106: 2143-2156, 2014
General anesthetics are known to cause depression of the freezing point of transitions in biomembranes. This is a consequence of ideal mixing of the anesthetic drugs in the membrane fluid phase and exclusion from the solid phase. Such a generic law provides physical justification of the famous Meyer-Overton rule.
Graesboll, Kaare   +2 more
arxiv   +4 more sources

Strategies to Improve Equitable Access to Early Osteoarthritis Diagnosis and Management: An updated Review

open access: yesArthritis Care &Research, EarlyView., 2023
Though osteoarthritis (OA) affects millions of people worldwide, many fail to access recommended early, person‐centered OA care, particularly women who are disproportionately impacted by OA. A prior review identified few strategies to improve equitable access to early diagnosis and management for multiple disadvantaged groups.
Angela Abenoja   +9 more
wiley   +1 more source

Safety of local anesthetics

open access: yesAnais Brasileiros de Dermatologia, 2020
Local anesthetics are essential medications for the conduction of dermatological procedures. They stop the depolarization of nerve fibers and are divided into two main categories, the amide and ester types. Systemic toxicity with reflex on the central nervous and cardiovascular systems is their most feared adverse reactions, and the anaphylactic ...
Ana Carolina Figueiredo Pereira Cherobin   +1 more
openaire   +6 more sources

Local anesthetics for the Nephrologist [PDF]

open access: yesClinical Kidney Journal, 2021
Abstract Several specialists in medicine use local anesthetics. In patients with kidney disease, these agents are used during catheter insertions for hemodialysis and peritoneal dialysis, arteriovenous fistula and graft procedures, kidney transplantation, parathyroidectomy, kidney biopsies, and dental and skin procedures.
Nupur N Uppal   +5 more
openaire   +2 more sources

Benzonatate as a local anesthetic

open access: yesPLOS ONE, 2023
Introduction Benzonatate is an FDA-approved antitussive agent that resembles tetracaine, procaine, and cocaine in its chemical structure. Based on structural similarities to known local anesthetics and recent findings of benzonatate exerting local anesthetic-like effects on voltage-gated sodium channels in vitro, we hypothesized that benzonatate will ...
Anna McGuire   +4 more
openaire   +4 more sources

Topography‐Supported Nanoarchitectonics of Hybrid Scaffold for Systematically Modulated Bone Regeneration and Remodeling

open access: yesAdvanced Functional Materials, Volume 32, Issue 51, December 16, 2022., 2022
In order to enhance the mechanical durability and biocompatibility of orthopedic implants, additively manufactured polyetheretherketone is reinforced with internal titanium dioxide nanoparticles via dopamine‐induced polymerization and additionally coated with hydroxyapatite using radiofrequency magnetron sputtering.
Tae‐Sik Jang   +15 more
wiley   +1 more source

Activated Platelet‐Targeted IR780 Immunoliposomes for Photothermal Thrombolysis

open access: yesAdvanced Functional Materials, Volume 33, Issue 4, January 20, 2023., 2023
Acute thrombosis is the underlying cause of myocardial infarction and stroke with high morbidity and mortality. Activated platelets are predominant components of acute thrombosis. Activated platelet‐targeted IR780 immunoliposomes present a promising delivery system for localized and potentially bleeding‐free photothermal therapy of acute thrombosis ...
Ahmed Refaat   +7 more
wiley   +1 more source

Clinical pain evaluation with intraoral vibration device during local anesthetic injections [PDF]

open access: yes, 2015
Objectives: To evaluate the clinical pain during local anesthetic injection using such intra-oral device. Study Design: A comparative split-mouth clinical study to evaluate clinical pain was conducted among the subjects who required bilateral local ...
Bhardwaj, Savita   +4 more
core   +2 more sources

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