Results 111 to 120 of about 4,692,515 (283)
Advanced Healthcare Materials, Volume 14, Issue 17, July 4, 2025.A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang +10 more
wiley +1 more source
Progress of Immune‐Inducible Biomaterials for Post‐Ablation Cancers
Advanced Healthcare Materials, EarlyView.The presence of residual tumors after ablative therapies poses a significant challenge, generally resulting in recurrence and metastases. This review offers a concise overview of immune‐inducible biomaterials from the perspective of the cancer‐immunity cycle, and how they enhance antitumor immunity through diverse mechanisms following ablative ...
Shuangshuang Zhao +7 more
wiley +1 more source
Immunosuppressive Formulations for Immunological Defense against Traumatic Brain Injury
Advanced Healthcare Materials, EarlyView.A novel subcutaneous formulation combining alpha‐ketoglutarate, glycolysis inhibitor PFK15, and a myelin peptide reduces inflammation in a mouse TBI model. This formulation promotes regulatory immune cells, enhances autophagy, and improves motor function, suggesting its potential as a prophylactic immunosuppressive therapy to mitigate TBI‐induced ...
Kelly Lintecum +28 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan +13 more
wiley +1 more source
Ultra‐Tiny Gelatin Nanoparticles‐Assisted 3D Stem Cell Spheroids for Engineering Tissue Regeneration
Advanced Healthcare Materials, EarlyView.GNPs effectively guide the formation of structurally compact and functionally enhanced stem cell spheroids. This GNP‐assisted 3D culture system improves cell–cell and cell‐ECM interactions, leading to superior viability and complexity. Time‐dependent regenerative potential is demonstrated in both bone and skin defects, positioning GNP‐spheroids as a ...
Dream Kim +7 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.A poly(hydroxy‐oxazolidone) (PHOx) is synthesized from CO2‐based precursors, enabling the up‐cycling of this waste material. After synthesis, PHOx shows thermoplastic properties, and can therefore be processed by many temperature‐dependent techniques. PHOx is hemocompatible, anti‐adhesive, and biocompatible, which is demonstrated in vitro and in vivo ...
Sofia F. Melo +11 more
wiley +1 more source
Advances in the use of local anesthetic extended-release systems in pain management
Drug DeliveryPain management remains among the most common and largely unmet clinical problems today. Local anesthetics play an indispensable role in pain management.
Yulu Chen +6 more
doaj +1 more source
1-dialkylaminoalyl 2-alkyl 3-aminophalates as Local Anesthetics [PDF]
, 1942 F. F. Blicke, OSTUK I. CHIEKO
openalex +1 more source
Advanced Materials, EarlyView.Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll +16 more
wiley +1 more source