Results 41 to 50 of about 4,859,005 (380)
Lipid Emulsion in the Successful Resuscitation of Local Anesthetic Toxicity after Ankle Block [PDF]
Korean Journal of Critical Care Medicine, 2014 Unexpected occurrence of local anesthetic toxicity is not rare and can cause fatal complications that do not respond to any known drug of intervention.
Sang Hee Park +5 more
doaj +1 more source
Computer-controlled local anesthetic delivery for painless anesthesia: a literature review
Journal of dental anesthesia and pain medicine, 2016 Local anesthesia is administered to reduce pain during dental treatments, but may itself cause pain and contribute to increased dental fear. Computer-controlled local anesthetic delivery (CCLAD) is one the method to reduce patient pain during local ...
Eun-Jung Kwak +5 more
semanticscholar +1 more source
THE PHARMACOLOGY OF THE LOCAL ANESTHETICS [PDF]
Journal of the American Medical Association, 1919 Acute intoxication in man from the use of the local anesthetics is far more common than is indicated by the number of recorded cases. We undertook to investigate the causes of such intoxication, and sought to find means of avoiding it, or combating it when it arises.
Robert A. Hatcher, Cary Eggleston
openaire +2 more sources
Indian Journal of Pain, 2014 Aim: The aim of this study was to evaluate and compare the Pain Perception and Procedural Tolerance (PPPT) by the pediatric patients, while experiencing ′Computer Controlled Local Anesthetic Technique′ (CCLAD, Wand) and ′Conventional local anesthetic ...
Rahul Goyal, B Nandlal, Prashanth
doaj +1 more source
Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels [PDF]
, 2008 Antiarrhythmics, anticonvulsants, and local anesthetics target voltage-gated sodium channels, decreasing excitability of nerve and muscle cells. Channel inhibition by members of this family of cationic, hydrophobic drugs relies on the presence of highly ...
Ahern, Christopher A. +3 more
core +2 more sources
Local anesthetic toxicity: acute and chronic management
Acute Medicine & Surgery, 2017 Local anesthetics are commonly used medicines in clinical settings. They are used for pain management during minor interventional treatments, and for postoperative care after major surgeries. Cocaine is the well‐known origin of local anesthetics, and the
Kenichi Sekimoto, M. Tobe, S. Saito
semanticscholar +1 more source
BMC Anesthesiology, 2019 Background Continuous epidural infusion (CEI) has some disadvantages, such as increased local anesthetic consumption and limited area of anesthetic distribution.
M. Higashi +4 more
doaj +1 more source
Successful lipid rescue of local anesthetic systemic toxicity following peribulbar block
Medical Journal of Dr. D.Y. Patil University, 2015 Local anesthesia is commonly used to perform cataract surgery. We present a case in which local anesthesia systemic toxicity, which occurred after peribulbar block.
Vinayak S Pujari +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley +1 more source
PLoS ONE, 2015 Background The use of peripheral nerve blocks for anesthesia and postoperative analgesia has increased significantly in recent years. Adjuvants are frequently added to local anesthetics to prolong analgesia following peripheral nerve blockade.
M. Kirksey +3 more
semanticscholar +1 more source