Results 71 to 80 of about 97,085 (246)
Local anesthetics and their adjuncts [PDF]
Pediatric Anesthesia, 2011 SummaryLocal anesthetics (LA) block propagation of impulses along nerve fibers by inactivation of voltage‐gated sodium channels, which initiate action potentials (1). They act on the cytosolic side of phospholipid membranes. Two main chemical compounds are used, amino esters and amino amides. Amino esters are degraded by pseudocholinesterases in plasma.
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Palatal ulceration: A local anesthetic complication
Indian Journal of Health Sciences and Biomedical Research KLEU, 2017 The hard palate is one of the common sites of local complications following administration of local anesthetics. The hard, unyielding palatal tissues coupled with either forceful or excessive administration of solution, induction of trauma, use of ...
Urvashi Sharma
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Impact of hyaluronidase on anesthetic distribution in retrobulbar region following sub-Tenon anesthesia [PDF]
Vojnosanitetski Pregled, 2008 Background/Aim. Sub-Tenon's block is nowadays commonly used in ophthalmic surgery because of its safety and efficacy. The aim of this study was to investigate the distribution of the anesthetic solution with different amounts of hyaluronidase in the ...
Šurbatović Maja +5 more
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Is Cardiolipin the Target of Local Anesthetic Cardiotoxicity?
, 2010 SummaryBackground and objectivesLocal anesthetics are used broadly to prevent or reverse acute pain and treat symptoms of chronic pain. Local anesthetic-induced cardiotoxic reaction has been considered the accidental event without currently effective ...
Yuan, HongMei +10 more
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Local Toxicity from Local Anesthetic Polymeric Microparticles
Anesthesia and Analgesia, 2013 BACKGROUND:Local tissue injury from sustained-release formulations for local anesthetics can be severe. There is considerable variability in reporting of that injury.
J. B. McAlvin +4 more
semanticscholar +1 more source
Molecules, 2015 Some functionalized 1,2,4,5-tetrasubstituted imidazole derivatives were synthesized using a one-pot, four component reaction involving 1,2-diketones, aryl aldehydes, ammonium acetate and substituted aromatic amines.
Yan Ran, Ming Li, Zong-Ze Zhang
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Pain, 2018 Cocaine is a naturally occurring compound indigenous to the Andes Mountains, West Indies, and Java. It was the first anesthetic to be discovered and is the only naturally occurring local anesthetic; all others are synthetically derived.
Carol L. Schroeder +1 more
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Local anesthetic inhibition of a bacterial sodium channel
The Journal of General Physiology, 2012 Recent structural breakthroughs with the voltage-gated sodium channel from Arcobacter butzleri suggest that such bacterial channels may provide a structural platform to advance the understanding of eukaryotic sodium channel gating and pharmacology.
Sora Lee, S. Goodchild, C. Ahern
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, 2002 P(論文)This study investigated whether or not lidocaine, one of the most widely used local anesthetics in dentistry, reacts with xanthine oxidase and generates superoxide radicals (O_2^) and/or some other oxygen radicals.
佐藤, 尚武, 26479
core
Pain Physician, 2003 The incidence of inadequate analgesia despite technically well performed injections led our clinic to prospectively test patients for response to a variety of local aesthetics. Skin testing was performed on the skin of the forearm away from the site of pathology. Patients were asked to identify "which is the most numb" of the skin wheals. Although most
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