Results 81 to 90 of about 97,085 (246)

Chlorpromazine as a Possible Local Anesthetic in Dentistry

open access: yes, 1971
The tranquilizer chlorpromazine has been shown to be a potent local anesthetic. In this study chlorpromazine was injected into the mandibular gingiva of dogs to study possible irritating effects on the oral tissue.
W.H. Bowles
core   +1 more source

Lipids in local anesthetic toxicity [PDF]

open access: yes, 2015
INTRODUCTION: With the advent of long-lasting local anesthetics, local and regional anesthesia gained considerable impetus and the use of these techniques has become increasingly widespread.
Dreyer, Elisabeth   +5 more
core   +1 more source

THE PHARMACOLOGY OF THE LOCAL ANESTHETICS [PDF]

open access: yesJournal of the American Medical Association, 1919
Acute intoxication in man from the use of the local anesthetics is far more common than is indicated by the number of recorded cases. We undertook to investigate the causes of such intoxication, and sought to find means of avoiding it, or combating it when it arises.
openaire   +1 more source

Potentially unsafe doses of local anesthetics in axillary brachial plexus block: A single-center retrospective cohort study.

open access: yesPLoS ONE
Local anesthetic systemic toxicity is a rare but potentially life-threatening complication of regional anesthesia that can occur when high doses of local anesthetics are administered.
Mélanie Suppan   +2 more
doaj   +1 more source

Continuous Femoral Nerve Blocks: Decreasing Local Anesthetic Concentration to Minimize Quadriceps Femoris Weakness

open access: yesAnesthesiology, 2012
Background: Whether decreasing the local anesthetic concentration during a continuous femoral nerve block results in less quadriceps weakness remains unknown.
Maria Bauer   +11 more
semanticscholar   +1 more source

The effects of preadministration of local anesthetic on pulsed radiofrequency

open access: yes, 2018
Background/aim: Pulsed radiofrequency (PRF) has been reported to be a safe and reliable method for the management of a variety of chronic pain syndromes.
Kurcaloglu, Mustafa   +6 more
core   +1 more source

Anesthetic Agents of Plant Origin: A Review of Phytochemicals with Anesthetic Activity

open access: yesMolecules, 2017
The majority of currently used anesthetic agents are derived from or associated with natural products, especially plants, as evidenced by cocaine that was isolated from coca (Erythroxylum coca, Erythroxylaceae) and became a prototype of modern local ...
Hironori Tsuchiya
doaj   +1 more source

Local anesthetic failure associated with inflammation: verification of the acidosis mechanism and the hypothetic participation of inflammatory peroxynitrite

open access: yes, 2008
Takahiro Ueno1, Hironori Tsuchiya2, Maki Mizogami1, Ko Takakura11Department of Anesthesiology, Asahi University School of Dentistry, Mizuho, Gifu, Japan; 2Department of Dental Basic Education, Asahi University School of Dentistry, Mizuho, Gifu ...
Maki Mizogami   +3 more
core  

Pharmacodynamic responses of exogenous epinephrine during mandibular third molar surgery

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
Background: The systemic effects attributable to the injection of dental local anesthetic solutions have been the subject of discussion for many years.
Sivaraj Sivanmalai   +5 more
doaj   +1 more source

Intravenous lipid emulsion for treatment of local anesthetic toxicity

open access: yes, 2010
M Caroline Kosh, April D Miller, Jill E Michels, , Department of Clinical Pharmacy and Outcomes Sciences, South Carolina College of Pharmacy, University of South Carolina Campus, Columbia, South Carolina, USADate of Preparation: 14th July 2010 Conflict ...
Jill E Michels   +2 more
core  

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