Results 81 to 90 of about 91,235 (267)

Buckling‐Resistant and Trace‐Stacked (BRATS) Design Enables Aid‐Free Implantation of Flexible Multielectrode Array with Minimized Inflammatory Tissue Response

open access: yesAdvanced Functional Materials, EarlyView.
Buckling‐resistant and trace‐stacked (BRATS) intracortical microelectrode arrays (MEAs) eliminate the need for insertion aid and complex surgical setup, resulting in minimal inflammatory tissue response, compared to conventional flexible MEAs inserted with aid. Trace stacking effectively doubled the channel count without increasing the MEA shank width,
May Yoon Pwint, Delin Shi, X. Tracy Cui
wiley   +1 more source

A Bespoke Programmable Interpenetrating Elastomer Network Composite Laryngeal Stent for Expedited Paediatric Laryngotracheal Reconstruction

open access: yesAdvanced Functional Materials, EarlyView.
A programmable interpenetrating double‐network architecture, created via 3D‐TIPS printing and resin infusion, synergistically combines thermoplastic and thermosetting elastomers to balance structural rigidity and surface softness—crucial for paediatric laryngeal stents.
Elizabeth F. Maughan   +14 more
wiley   +1 more source

Local anesthetic systemic toxicity: current perspectives

open access: yesLocal and Regional Anesthesia, 2018
Kariem El-Boghdadly,1,2 Amit Pawa,1 Ki Jinn Chin3 1Department of Anaesthesia, Guy’s and St Thomas’ NHS Foundation Trust, London, UK; 2School of Medicine, King’s College London, London, UK; 3Department of Anesthesia, Toronto Western ...
El-Boghdadly K, Pawa A, Chin KJ
doaj  

Comparison of the Local Anesthetic Effect of Two Doses of Dexmedetomidine , 5µg and 10µg added to Intrathecal Hyperbaric Bupivacaine

open access: gold, 2022
Khalid Abaidullah   +5 more
openalex   +2 more sources

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

open access: yesAdvanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee   +4 more
wiley   +1 more source

Identification of an essential binding site for local anesthetics in the ‘side pockets´ of Kv1 channels [PDF]

open access: green, 2020
Aytuğ K. Kiper   +13 more
openalex   +1 more source

A Single‐Metal‐Doped Nanoplatform for Ferroptosis‐Driven cGAS‐STING Pathway Activation in Hepatocellular Carcinoma Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
The cGAS‐STING pathway boosts HCC antitumor immunity but lacks specific activation. Nanoplatform ZMRPF induces HCC ferroptosis via lipid ROS, releasing mtDNA. It synergizes with ZMRPF‐released Mn2⁺ to activate cGAS‐STING, amplifies antigen‐presenting cell activity, reverses HCC immunosuppression, and enables robust systemic antitumor immunity ...
Yuchen Zhang   +13 more
wiley   +1 more source

An Ionic Gelation Powder for Ultrafast Hemostasis and Accelerated Wound Healing

open access: yesAdvanced Functional Materials, EarlyView.
An ultrafast ionic gelation‐activated hemostatic powder (AGCL) forms a hydrogel within ≈1 s upon contact with blood‐derived calcium ions. The AGCL powder enables rapid hemorrhage control, strong tissue adhesion, and enhanced healing. The powder's pre‐crosslinked polymer network ensures high blood uptake and stability, offering effective treatment for ...
Youngju Son   +12 more
wiley   +1 more source

Can repeated exposure to morphine change the spinal analgesic effects of lidocaine in rats?

open access: yesJournal of Research in Medical Sciences, 2011
Background: Chronic opium exposure leads to altered response to opioid compounds. The aim of this study was to assess the behavioral effects of opium tolerance on the analgesic effects of intrathecal lidocaine in rats.
Ali Dabbagh   +4 more
doaj  

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