Results 171 to 180 of about 345,347 (366)
Sensory Encoding Alternates With Hippocampal Ripples across Cycles of Forebrain Spiking Cascades
Advanced Science, EarlyView.This study reveals widespread, coordinated brain activity during passive visual stimulation in mice. Sensory coding, phase‐locked with the periodic dynamics, shows an inverse relationship to hippocampal ripples. The results suggest that periodic brain activity spurs alteration between two distinct operational modes of brain, facilitating exteroceptive ...
Yifan Yang +4 more
wiley +1 more source
Advanced Science, EarlyView.In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa +6 more
wiley +1 more source
Materials for Controlled Release of Local Anesthetics. [PDF]
ChemMedChem, 2023 Li Y, Owens GE, Kohane DS.
europepmc +1 more source
The Toxicity and Local Anesthetic Activity of Three New Biphenyl Derivatives. J [PDF]
, 1941 Edwin J. Fellows
openalex +1 more source
Advanced Science, EarlyView.The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu +13 more
wiley +1 more source
Implementation of a Verification of Local Anesthetics (VoLS) Tool to Reduce Local Anesthetic Systemic Toxicity [PDF]
Background: Local anesthetic systemic toxicity (LAST) is a life-threatening condition resulting from the overdose of local anesthetics (LA). Untreated LAST can lead to seizures, cardiopulmonary collapse, and possible death. Local Problem: Our project was
Aguirre, Pedro G, SRNA +5 more
core +1 more source
THE USE OP CELL SUSPENSIONS TO DETERMINE THE CYTOTOXICITY OF LOCAL ANESTHETICS
, 1949 Lloyd A. Gittelson
openalex +1 more source
Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy
Advanced Science, EarlyView.This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan +11 more
wiley +1 more source
Advanced Science, EarlyView.A type of polydopamine (PDA) nanogel decorated adhesive and responsive hierarchical microcarriers for ALA delivery and deafness prevention. PDA@microcarriers can protect the encapsulated drugs from external disturbances and prolong their retention time in the inner ear.
Hong Chen +8 more
wiley +1 more source