Results 11 to 20 of about 345,347 (366)

The thermodynamics of general and local anesthesia [PDF]

open access: yesBiophys. J. 2014, 106: 2143-2156, 2014
General anesthetics are known to cause depression of the freezing point of transitions in biomembranes. This is a consequence of ideal mixing of the anesthetic drugs in the membrane fluid phase and exclusion from the solid phase.
Graesboll, Kaare   +2 more
core   +3 more sources

Characterization of Large Scale Functional Brain Networks During Ketamine-Medetomidine Anesthetic Induction [PDF]

open access: yesarXiv, 2016
Several experiments evidence that specialized brain regions functionally interact and reveal that the brain processes and integrates information in a specific and structured manner. Networks can be used to model brain functional activities constituting a
Padovani, Eduardo C.
core   +1 more source

Impact of gadolinium-based MRI contrast agent and local anesthetics co-administration on chondrogenic gadolinium uptake and cytotoxicity [PDF]

open access: yesHeliyon
The gadolinium-based contrast agent DOTA-Gd is clinically used in combination with local anesthetics for direct magnetic resonance arthrography. It remains unclear whether gadolinium uptake into cartilage is influenced by co-administration of bupivacaine
Alexander Zimmerer   +8 more
doaj   +2 more sources

Research advances in the roles of local anesthetics in tumor metastasis and recurrence [PDF]

open access: yesJichu yixue yu linchuang, 2022
Anesthetics are commonly used in the perioperative treatment of tumor. The choice of different anesthetics and anesthesia techniques will affect the proliferation, metastasis, recurrence and prognosis of cancer.
LIU Chang, GUO Xiang-yang
doaj   +1 more source

Knowledge and awareness about local anesthetics used in endodontic procedures among dental students [PDF]

open access: yes, 2022
Introduction: Local anesthetics are a special group of drugs that cause reversible loss of sensation. They are the most commonly used drug in dentistry.
Imtiaz, Taanya, Khandelwal, Akshay
core   +1 more source

Direct Cytotoxic and Indirect, Immune-Mediated Effects of Local Anesthetics Against Cancer

open access: yesFrontiers in Oncology, 2022
Local anesthetics are frequently employed during surgery in order to control peri- and postoperative pain. Retrospective studies have revealed an unexpected correlation between increased long-term survival and the use of local anesthetics during ...
Alejandra Wu Chuang   +9 more
doaj   +1 more source

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation

open access: yesStem Cell Research & Therapy, 2021
Background A large number of preclinical studies have shown that local anesthetics have a direct inhibitory effect on tumor biological activities, including cell survival, proliferation, migration, and invasion. There are few studies on the role of local
Xiaoqing Fan   +7 more
doaj   +1 more source

Topics in Local Anesthetics [PDF]

open access: yes, 2021
The fascinating history of local anesthetics was born in the Andean Mountains with the use of Erythroxylum coca and has gradually evolved into a group of safe drugs in anesthesiology and pain medicine.

core   +1 more source

Differential effects and mechanisms of local anesthetics on esophageal carcinoma cell migration, growth, survival and chemosensitivity

open access: yesBMC Anesthesiology, 2020
Background Retrospective analysis and pre-clinical studies suggest that local anesthetics have anti-tumoral effects. However, the association between cancer recurrence and the use of local anesthesia is inconclusive and most reports are based on single ...
Guanhua Zhu   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy