Results 11 to 20 of about 47,127 (296)

Chiral Aspects of Local Anesthetics

open access: yesMolecules, 2020
Thanks to the progress made in chemical technology (particularly in the methodologies of stereoselective syntheses and analyses) along with regulatory measures, the number of new chiral drugs registered in the form of pure enantiomers has increased over ...
Ružena Čižmáriková   +4 more
doaj   +2 more sources

On controversial issues of systemic toxicity of local anesthetics

open access: yesВестник анестезиологии и реаниматологии, 2020
The letter draws attention to the provisions on the use of fat emulsion when systemic toxicity of local anesthetics develops that was published in the article titled Disputed Issues of Systemic Toxicity of Local Anesthetics.
R. E. Lakhin
doaj   +3 more sources

Sweet-Tasting Ionic Conjugates of Local Anesthetics and Vasoconstrictors

open access: yesMolecules, 2021
Local anesthetics are widely utilized in dentistry, cosmetology, and medicine. Local anesthesia is essential to providing a pain-free experience during dental and local surgeries as well as cosmetic procedures.
John K. Neubert   +9 more
doaj   +2 more sources

Disputed issues of systemic toxicity of local anesthetics

open access: yesВестник анестезиологии и реаниматологии, 2020
Objective: assessment of the "systemic toxicity of local anesthetics,” term validity, and a legal appraisal of the term “lipid resuscitation.” Regulatory documents and specialized literature devoted to the terminology of toxicity of local anesthetics ...
V. V. Unzhakov   +2 more
doaj   +3 more sources

Local anesthetics elicit immune-dependent anticancer effects

open access: yesJournal for ImmunoTherapy of Cancer, 2022
BACKGROUND: Retrospective clinical trials reported a reduced local relapse rate, as well as improved overall survival after injection of local anesthetics during cancer surgery.
Shuai Zhang   +14 more
doaj   +2 more sources

Potential Impact of Local Anesthetics Inducing Granulocyte Arrest and Altering Immune Functions on Perioperative Outcome [PDF]

open access: yes, 2021
Introduction: Local anesthetics (LAs) are frequently used during anesthesia; however, they may influence granulocyte function which in turn could modify immune responses in the perioperative period. Therefore, the aim of this study was to investigate the
Pfaehler, Sophie-Marie   +8 more
core   +1 more source

Minimum anesthetic volume in regional anesthesia by using ultrasound-guidance

open access: yesRevista Brasileira de Anestesiologia, 2016
The ultrasound guidance in regional anesthesia ensures the visualization of needle placement and the spread of Local Anesthetics. Over the past few years there was a substantial interest in determining the Minimum Effective Anesthetic Volume necessary to
Alessandro Di Filippo   +2 more
doaj   +3 more sources

Cytotoxicity of Local Anesthetics on Bone, Joint, and Muscle Tissues: A Narrative Review of the Current Literature

open access: yesJournal of Pain Research, 2023
Kaiwen Zhang, Meihong Li, Wenlong Yao, Li Wan Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of ChinaCorrespondence: Li Wan, Department of Anaesthesiology ...
Zhang K, Li M, Yao W, Wan L
doaj  

Local Anesthetics [PDF]

open access: yesJournal of Industrial & Engineering Chemistry, 1920
n ...
openaire   +4 more sources

Molecular and Physicochemical Aspects of Local Anesthetics Acting on Nicotinic Acetylcholine Receptor-containing Membranes [PDF]

open access: yes, 2002
Local anesthetics inhibit the ion channel activity of nicotinic acetylcholine receptors in a noncompetitive fashion. This inhibitory action is ascribed to two possible inhibitory mechanisms: an open-channel-blocking mechanism and/or an allosteric process
Blanton, Michael P., Arias, Hugo Rubén
core   +1 more source

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