Results 211 to 220 of about 4,751,276 (340)

Assessing α-Bisabolol as a Transmucosal Permeation Enhancer of Buccal Local Anesthetics. [PDF]

Pharmaceutics
do Couto RO, Thomaz DV, Duarte MPF, Lopez RFV, Pedrazzi V, de Freitas O, Tartaglia GM.   +6 more
europepmc   +1 more source

Role of Protein Synthesis in Recovery From Local Anesthetic-Induced Conduction Blockade

, 1969
Donald E. Knapp, SERGIO MEJ A
openalex   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

Orosomucoid 1 Ameliorates Temporomandibular Joint Osteoarthritis by Maintaining Cartilage Homeostasis

Advanced Science, EarlyView.
The present study identified the key protein ORM1 through the proteomic analysis of synovial fluid samples from patients with temporomandibular joint osteoarthritis (TMJOA), and demonstrated the important role of ORM1 in maintaining cartilage homeostasis via the suppression of VIM/MAPK/MMP signalling.
Dahe Zhang, Yuxin Zhang, Simo Xia, Lu Chen, Pei Shen, Chi Yang   +5 more
wiley   +1 more source

A Clinical Comparative Study of Dexmedetomidine, Dexamethasone, and Clonidine as Adjuvants to Local Anesthetics in Supraclavicular Brachial Plexus Blocks. [PDF]

Cureus
Yadav UP, Agrawal J, Singh A, Goyal P.
europepmc   +1 more source

Reduction of Bleeding by the Addition of Vasoconstrictor Drugs to Local Anesthetics

, 1962
Richard G. Fosburg
openalex   +2 more sources

Intraperitoneal Local Anesthetics Have Predominant Local Analgesic Effect: A Randomized, Double-blind Study

Anesthesiology, 2014
A. Perniola, A. Magnuson, K. Axelsson, Anil Gupta   +3 more
semanticscholar   +1 more source

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances

Advanced Science, EarlyView.
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch, Roberto De Luca, Richard L Spinieli, Enrico Rillosi, Renner C Thomas, Samuel Sailesh, Nishta Gangeddula, Janayna D Lima, Sathyajit S Bandaru, Elda Arrigoni, Agustin Melo‐Carrillo, Rami Burstein, Stephen Thankachan, Satvinder Kaur   +13 more
wiley   +1 more source

Effect of Dental Local Anesthetics on Reactive Oxygen Species: An In Vitro Study. [PDF]

Cureus
Kuroda H, Tsukimoto S, Kosai A, Komatsu N, Ouchi T, Kimura M, Sato-Boku A, Yoshida A, Yoshino F, Abe T, Shibukawa Y, Sanuki T.   +11 more
europepmc   +1 more source