Results 231 to 240 of about 86,163 (345)

Local Anesthetics in Diabetic Retinopathy Procedures: A Comprehensive Review With a Focus on Lidocaine-Based Pain Control. [PDF]

Cureus
Rezaei K, Riazi Esfahani P, Balen M, Nguyen TB, Farasat VP, Reddy AJ, Sheikh S.   +6 more
europepmc   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

Elucidating the Solubility Enhancement of Active Pharmaceutical Ingredients through Hydrotropy: A Case of Local Anesthetics. [PDF]

Mol Pharm
Nasrallah S, Wendler A, Hallweger SA, Kieslich G, Minceva M.   +4 more
europepmc   +1 more source

Combined low dose local anesthetics and opioids versus single use of LA for transurethral urological surgery: A meta-analysis

, 2015
Yifan Chi, Yu Ding, Ming Li, Li Chen, Qian Zhang, An Jiang   +5 more
openalex   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

The influence of Dexmedetomidine as an additive to local anesthetics in dental procedures: A systematic review. [PDF]

Med Oral Patol Oral Cir Bucal
Diniz DA, França AJ, Laureano-Filho JR, Pellizzer EP, Moraes SL, Vasconcelos BC.   +5 more
europepmc   +1 more source

Comparative evaluation of the local anesthetic activity of root extract of Anacyclus pyrethrum and its interaction at the site of injection in guinea pigs

, 2017
Kameshwaran Muralikrishnan, Sharath Asokan, PR Geetha Priya, KSyed Zameer Ahmed, G Ayyappadasan   +4 more
openalex   +1 more source

Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound

Advanced Science, EarlyView.
In this study, Qiu et al. found that low‐intensity ultrasound can directly activate sparse ultrasound‐sensitive neurons (UNs) in the primary visual cortex (V1) of deafened mice. The proportion of these sparse UNs is pressure‐dependent. Furthermore, ultrasound modulates visual circuitry with distinct excitatory and inhibitory effects.
Jiaru He, Jiejun Zhu, Xinxin Wang, Zihao Chen, Jin Yang, Zhen Yuan, Hongzhi Xu, Lei Sun, Zhihai Qiu   +8 more
wiley   +1 more source

Evaluation of diagnostic tests for immediate-type allergic reactions to amide group local anesthetics in children. [PDF]

Pediatr Allergy Immunol
Aslan S, Anıl H, Kaya M, Harmancı K.
europepmc   +1 more source

A Comparative Study between the Effect of Combined Local Anesthetic and Low-dose Ketamine with Local Anesthetic on Postoperative Complications after Impacted Third Molar Surgery

, 2015
Tejraj P. Kale
openalex   +1 more source